Thyroseq
Thyroseq® is an expanded gene classifier test designed for further evaluation of indeterminate thyroid nodules on fine needle aspiration (FNA). In particular, it is designed to further evaluate nodules that show atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) on cytology. It can also be used to risk-stratify nodules that show follicular neoplasm cytology 2.
The test is a multigene next-generation assay that evaluates for multiple mutations in thyroid cancer. Early results suggest that it offers increased sensitivity and specificity over standard gene expression classifier/AFIRMA testing for detection of cancer in these indeterminate nodules. The most recent iteration of the test is version 3 (as of late 2019). It uses DNA, mRNA, and miRNA markers for evaluation.
Related Radiopaedia articles
Interventional procedures
- introduction
- procedure overview
- neck
- thyroid gland
- breast
- chest
-
hepatobiliary
- liver
- biliary system
- splenic interventions
- gastrointestinal
- urogenital
- bladder
- kidney
- prostate
- musculoskeletal
-
arthrogram
- MR arthrogram
- CT arthrogram
- anesthetic arthrogram
- bone biopsy (CT-guided)
- shoulder (disambiguation)
-
elbow
- common extensor origin microtenotomy
- common flexor origin microtenotomy
- distal biceps tendon sheath injection
- elbow joint injection
- median nerve injection
- ulnar nerve injection
-
hip
- hip joint injection
- common hamstrings origin microtenotomy
- gluteus minimus/ medius tendon calcific tendinopathy barbotage
- greater trochanteric bursa injection
- iliopsoas tendon bursa injection
- lateral femoral cutaneous nerve of the thigh injection
- piriformis injection
- quadratus femoris injection
-
knee
- common peroneal (fibular) nerve injection
- knee joint injection
- patella tendon microtenotomy
- quadriceps tendon microtenotomy
- tibial nerve injection
-
ankle
- achilles hydrodilation & microtenotomy
- ankle joint injection
- extensor tendon sheath injection
- flexor tendon sheath injection
- os trigonum injection
- peroneal tendon sheath injection
- subtalar joint injection
- tibial nerve injection
-
arthrogram
- spine
- vascular