Citation, DOI, disclosures and article data
Citation:
Gaillard F, Knipe H, d, et al. Classification system for midline abnormalities of the brain and skull. Reference article, Radiopaedia.org (Accessed on 09 Mar 2025) https://doi.org/10.53347/rID-15855
Disclosures:
At the time the article was last revised Henry Knipe had the following disclosures:
- Integral Diagnostics, Shareholder (ongoing)
- Micro-X Ltd, Shareholder (ongoing)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Henry Knipe's current disclosures
Classification systems for midline abnormalities of the brain and skull are varied and constantly changing as the underlying embryology and genetics are uncovered.
Classification
A relatively simple and robust classification system is based on the location of abnormalities, proposed by Nuñez et al. in 2011 1, always remembering that midline abnormalities often 'travel in packs'.
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1. Nuñez S, Mantilla M, Bermúdez S. Midline Congenital Malformations of the Brain and Skull. Neuroimaging Clin N Am. 2011;21(3):429-82, vii. doi:10.1016/j.nic.2011.05.001 - Pubmed
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