Intracranial arterial fenestration
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At the time the article was created Jeremy Jones had no recorded disclosures.
View Jeremy Jones's current disclosuresAt the time the article was last revised Travis Fahrenhorst-Jones had no financial relationships to ineligible companies to disclose.
View Travis Fahrenhorst-Jones's current disclosures- Intracranial artery fenestration
- Fenestration of intracranial arteries
Intracranial arterial fenestration refers to segmental duplication of the intracranial arteries. They may be contrasted to arterial duplication, which consists of two distinct vessels with separate origins and no downstream convergence. They are rare anomalies, felt to result from incomplete fusion of primitive embryologic vessels.
Fenestration is the luminal division of the vessel into two separate and parallel channels which rejoin distally 1. Each channel has distinct endothelial and muscularis layers, may be differently sized, and may share adventitial layer depending on degree of embryological fusion 3. Although a fenestration is usually of considered to be of minimal significance, there is an association with aneurysm formation near proximal part of fenestration 2. This is hypothesized to be secondary to focal defects in media layer near sites of channel divergence/convergence 4,5.
Fenestration is more common in the posterior circulation. The rate of fenestrations based on published angiographic series has been much lower than that at cadaveric series. Reported incidence of intracranial fenestration on imaging series is 3:
intracranial internal cartoid artery: rare
-
A1 segment: ~2%
A2 segment: ~2% (autopsy series)
basilar artery fenestration: ~0.6%
vertebral artery: ~1%
References
- 1. Gailloud P, Albayram S, Fasel JH et-al. Angiographic and embryologic considerations in five cases of middle cerebral artery fenestration. AJNR Am J Neuroradiol. 2002;23 (4): 585-7. AJNR Am J Neuroradiol (full text) - Pubmed citation
- 2. Uchino A, Takase Y, Nomiyama K, Egashira R, Kudo S. Fenestration of the Middle Cerebral Artery Detected by MR Angiography. Magn Reson Med Sci. 2006;5(1):51-5. doi:10.2463/mrms.5.51 - Pubmed
- 3. Dimmick SJ, Faulder KC. Normal variants of the cerebral circulation at multidetector CT angiography. Radiographics. 2009;29 (4): 1027-43. Radiographics (full text) - doi:10.1148/rg.294085730 - Pubmed citation
- 4. Cooke DL, Stout CE, Kim WT, Kansagra AP, Yu JP, Gu A, Jewell NP, Hetts SW, Higashida RT, Dowd CF, Halbach VV. Cerebral arterial fenestrations. (2014) Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences. 20 (3): 261-74. doi:10.15274/INR-2014-10027 - Pubmed
- 5. Sanders W, Sorek P, Mehta B. Fenestration of Intracranial Arteries with Special Attention to Associated Aneurysms and Other Anomalies. AJNR Am J Neuroradiol. 1993;14(3):675-80. PMC8333398 - Pubmed
Incoming Links
- Arterial fenestration
- ACOM and right M1 fenestrations
- Basilar artery fenestration
- Posterior cerebral artery fenestration
- Vertebral artery fenestration
- Lateral medullary syndrome
- Qudrigeminal cistern lipoma and multiple anatomic variations of intracranial arteries
- Vein of Trolard thrombosis with venous infarction (CT perfusion)
- Fenestration of vertebral artery
- Anterior comminucating artery fenestration complex with saccular aneurysm
- Anterior communicating artery fenestration
- Anterior cerberal artery fenestration
- Anterior cerebral arterial variations
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- Acom artery fenestration - complex
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