Littoral cell angioma of the spleen

Dr Dan J Bell and Radswiki et al.

Littoral cell angioma of the spleen (LCA) is a rare and relatively recently (1991) described vascular tumour of the spleen.

Littoral cell angiomas may occur at any age and have no gender predilection.

Typically, patients with littoral cell angioma are found to have a splenic abnormality when they are being evaluated for laboratory evidence of anaemia or thrombocytopenia.

Reported associations include: 

Ultrasound, CT, and MR images usually demonstrate splenomegaly and multiple lesions of similar size and appearance.

As most patients are symptomatic from anaemia and thrombocytopenia and because imaging findings are non-specific, splenectomy is usually performed for definitive histological diagnosis and treatment. At present biologic behaviour has not been firmly established.

The differential is essentially that of multiple splenic lesions.

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Article information

rID: 12455
Synonyms or Alternate Spellings:
  • Littoral cell angioma of spleen
  • Littoral cell angiomas of spleen
  • Littoral cell angiomas of the spleen
  • Splenic Littoral cell angioma
  • Littoral cell angioma of the spleen (LCA)

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