Shortening of the fourth/fifth metacarpals

Last revised by Rohit Sharma on 17 Feb 2025

Shortening of the fourth/fifth metacarpals (brachymetacarpia) and less commonly metatarsals (brachymetatarsia) is seen in a variety of apparently disparate conditions. 

Pathology

Etiology

Common causes 2:

Uncommon causes 2:

Isolated shortening of the 5th metacarpals has been described in a familial variant of type 1 diabetes mellitus 3.

Radiographic features

Plain radiograph

Hand x-rays readily identify the abnormality and can be assessed by drawing a line along the heads of the 4th and 5th metacarpals. If this line intersects the head of the 3rd metacarpal then shortening is deemed to be present. 

Thus, shortened 4th metacarpal is the key to this finding. It is known as the metacarpal sign. It is important to note that a positive sign can be seen in up to 10% of normal individuals 4.

Cases and figures

  • Figure 1: positive metacarpal sign
  • Case 1: post-traumatic
  • Figure 2: negative metacarpal sign
  • Case 2: positive metacarpal sign
  • Case 3: isolated unilateral shortened 5th metacarpal
  • Case 4: Turner syndrome
  • Case 5: Turner syndrome - hand
  • Case 6: bilateral short 5th metacarpals
  • Case 7: short fourth metacarpal
  • Case 8: short 4th/5th metacarpal
  • Case 9: short 5th metacarpal
  • Case 10: pseudohypoparathyroidism
  • Case 11: short 5th metacarpal
  • Case12: positive metacarpal sign
  • Case 13
  • Case 14
  • Case 15
  • Case 16
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