Autologous blood clot - embolization agent

Changed by Yaïr Glick, 4 Jul 2023
Disclosures - updated 5 Jun 2023: Nothing to disclose

Updates to Article Attributes

Body was changed:

The autologous blood clot or patch is a temporary embolisation agent adapted for large vessel occlusion procedures such as haemostatic embolisations but can also be used as a seal for a biopsy trajectory during lung and hepatic biopsies.

Advantages
  • biocompatible

  • inexpensive

  • simple, rapid, and easy preparation

Disadvantages

Short embolisation duration with vessel recanalisation in hours/days, due to fibrinolysis.

Indications

Vascular interventional procedures

Percutaneous interventional procedures

  • biopsy trajectory seal after a lung biopsy to avoid pneumothorax7

  • liver biopsy trajectory seal to prevent bleeding

  • autologous blood patch pleurodesis treatment for persistent pneumothorax in dogs8

Urology procedures

Lower calyceal occlusion to prevent stone fragment reaccumulation after retrograde intra-renalintrarenal surgery for lower calyceal stones9.

Neurology

It could be used as an epidural blood patch to prevent headaches following lumbar puncture.

Preparation

  1. collect the amount of whole blood needed in a syringe (e.g. 10 ccml, 20 ccml)

  2. at room temperature, leave the blood indisturbedundisturbed for 15–30 minutes to allow clot formation

  3. discard the supernatentsupernatant (serum)

  4. opacify the clot using sterile tantalum powder or iodinated contrast (optional)

  5. inject the blood clot ininto target destination

  • -<p>The <strong>autologous blood clot or patch </strong>is a temporary <a href="/articles/embolization-agents" title="Embolization agents">embolisation agent</a> adapted for large vessel occlusion procedures such as haemostatic embolisations but can also be used as a seal for biopsy trajectory during lung and hepatic biopsies.</p><h5>Advantages</h5><ul>
  • +<p>The <strong>autologous blood clot </strong>or<strong> patch </strong>is a temporary <a href="/articles/embolization-agents" title="Embolization agents">embolisation agent</a> adapted for large vessel occlusion procedures such as <a href="/articles/haemostatic-embolisations" title="haemostatic embolisations">haemostatic embolisations</a> but can also be used as a seal for a biopsy trajectory during lung and hepatic biopsies.</p><h5>Advantages</h5><ul>
  • -<li><p>gastroduodenal artery during gastroduodenal bleeding<sup>1</sup></p></li>
  • -<li><p>small branch perforation due to percutaneous coronary intervention<sup>2</sup></p></li>
  • -<li><p>renal artery pseudoaneurysm<sup>3,4</sup></p></li>
  • +<li><p><a href="/articles/gastroduodenal-artery" title="Gastroduodenal artery">gastroduodenal artery</a> during gastroduodenal bleeding <sup>1</sup></p></li>
  • +<li><p>small branch perforation due to percutaneous coronary intervention <sup>2</sup></p></li>
  • +<li><p><a href="/articles/renal-artery-pseudoaneurysm" title="Renal artery pseudoaneurysm">renal artery pseudoaneurysm</a> <sup>3,4</sup></p></li>
  • -<li><p>penile artery embolisation<sup>5 </sup>- in post-traumatic priapism</p></li>
  • -<li><p><a href="/articles/transcatheter-arterial-chemoembolisation" title="Transcatheter arterial chemoembolization (TACE)">transcatheter arterial chemoembolization of HCC</a><sup>6</sup></p></li>
  • +<li><p><a href="/articles/penile-artery" title="penile artery">penile artery</a> embolisation <sup>5</sup> in post-traumatic priapism</p></li>
  • +<li><p><a href="/articles/transcatheter-arterial-chemoembolisation" title="Transcatheter arterial chemoembolization (TACE)">transcatheter arterial chemoembolization of HCC</a> <sup>6</sup></p></li>
  • -<li><p>biopsy trajectory seal after a lung biopsy to avoid pneumothorax<sup>7</sup></p></li>
  • -<li><p>liver biopsy trajectory seal to prevent bleeding</p></li>
  • -<li><p>autologous blood patch pleurodesis treatment for persistent pneumothorax in dogs<sup>8</sup></p></li>
  • -</ul><p><strong>Urology procedures</strong></p><p>Lower calyceal occlusion to prevent stone fragment reaccumulation after retrograde intra-renal surgery for lower calyceal stones<sup>9</sup>.</p><p><strong>Neurology</strong></p><p>It could be used as an epidural blood patch to prevent headaches following lumbar puncture.</p><h4>Preparation</h4><ol>
  • -<li><p>collect the amount of whole blood needed in a syringe (e.g. 10 cc, 20 cc)</p></li>
  • -<li><p>at room temperature, leave the blood indisturbed for 15–30 minutes to allow clot formation</p></li>
  • -<li><p>discard the supernatent (serum)</p></li>
  • -<li><p>opacify the clot using sterile tantalum powder or iodinated contrast (optional)</p></li>
  • -<li><p>inject the blood clot in target destination</p></li>
  • +<li><p>biopsy trajectory seal after a <a href="/articles/ct-guided-thoracic-biopsy" title="CT guided lung biopsy">lung biopsy</a> to avoid pneumothorax <sup>7</sup></p></li>
  • +<li><p><a href="/articles/liver-biopsy-percutaneous" title="Liver biopsy (percutaneous)">liver biopsy</a> trajectory seal to prevent bleeding</p></li>
  • +<li><p>autologous blood patch <a href="/articles/pleurodesis" title="Pleurodesis">pleurodesis</a> treatment for persistent pneumothorax in dogs <sup>8</sup></p></li>
  • +</ul><p><strong>Urology procedures</strong></p><p>Lower calyceal occlusion to prevent stone fragment reaccumulation after retrograde intrarenal surgery for lower calyceal <a href="/articles/urolithiasis" title="Kidney stones">stones</a> <sup>9</sup>.</p><p><strong>Neurology</strong></p><p>It could be used as an epidural blood patch to prevent headaches following <a href="/articles/lumbar-puncture" title="Lumbar puncture">lumbar puncture</a>.</p><h4>Preparation</h4><ol>
  • +<li><p>collect the amount of whole blood needed in a syringe (e.g. 10 ml, 20 ml)</p></li>
  • +<li><p>at room temperature, leave the blood undisturbed for 15–30 minutes to allow clot formation</p></li>
  • +<li><p>discard the supernatant (serum)</p></li>
  • +<li><p>opacify the clot using sterile tantalum powder or <a href="/articles/iodinated-contrast-media-1" title="Iodinated contrast media">iodinated contrast</a> (optional)</p></li>
  • +<li><p>inject the blood clot into target destination</p></li>

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