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Bosniak classification of cystic renal masses (version 2019)

The Bosniak classification of cystic renal masses (version 2019), or usually simply Bosniak classification, version 2019,  is a proposed update of the classic/current Bosniak criteria. The update hopes to improve on the classification's predictive power for malignancy and minimize the number of benign lesions undergoing treatment.

An important note is that the Bosniak classification (version 2019) is a proposed update that has had some small validation studies with mixed results 2-4 and its use in clinical practice is not widespread (c. 2021). 

The new version has separate CT and MRI criteria:

Class I

  • well-defined thin (≤2 mm) smooth wall
  • homogeneous simple fluid (-9 to 20 HU)
  • no septa or calcification
  • the wall may enhance after administration of contrast

Class II

  • six types all with thin (≤2 mm) smooth walls
    1. cystic masses with thin (≤2 mm) and few (1-3) septa
      • septa and wall may enhance
      • may have calcifications of any type (although if the calcification is thick and nodular consider MRI before assigning a class)
    2. homogeneous hyperattenuating (≥70 HU) masses on noncontrast CT
    3. homogeneous nonenhancing masses >20 HU at renal mass protocol CT
      • may have calcifications of any type (although if the calcification is thick and nodular consider MRI before assigning a class)
    4. homogeneous masses (-9 to 20 HU at noncontrast CT)
    5. homogeneous masses (21 to 30 HU at portal venous phase CT)
    6. homogeneous low attenuation masses that are too small to characterize

Class IIF

  • smooth minimally thickened (3 mm) enhancing wall
  • smooth minimal thickening (3 mm) of one or more enhancing septa
  • many (≥4) smooth thin (≤2 mm) enhancing septa

Class III

  • one or more walls or septa that are
    • enhancing thick (≥4 mm width) 
    • enhancing irregular (displaying ≤3 mm obtusely margined convex protrusion[s]) 

Class IV

  • one or more enhancing nodule(s) 
    • ≥4 mm convex protrusion with obtuse margins 
    • a convex protrusion of any size that has acute margins

Class I

  • well-defined thin (≤2 mm) smooth wall
  • homogeneous simple fluid (signal intensity similar to CSF)
  • no septa or calcification
  • the wall may enhance after administration of contrast

Class II

  • three types all with thin (≤2 mm) smooth walls
    1. cystic masses with 
      • thin (≤2 mm) and few (1-3) enhancing septa
      • any nonenhancing septa
      • calcification of any type
    2. homogeneous masses markedly hyperintense at T2W (similar to CSF) at noncon MRI
    3. homogeneous masses markedly hyperintense at T1W (approximately 2.5x normal parenchymal signal intensity) at noncontrast MRI

Class IIF

  • two types:
    1. cystic masses with 
      • smooth minimally thickened (3 mm) enhancing wall
      • smooth minimal thickening (3 mm) of one or more enhancing septa
      • many (≥4) smooth thin (≤2 mm) enhancing septa
    2. cystic masses that are heterogeneously hyperintense at unenhanced fat-saturated T1W imaging

Class III

  • one or more walls or septa that are
    • enhancing thick (≥4 mm width)
    • enhancing irregular (displaying ≤3 mm obtusely margined convex protrusion[s]) 

Class IV

  • one or more enhancing nodule(s) 
    • ≥4 mm convex protrusion with obtuse margins
    • a convex protrusion of any size that has acute margins

Class I

  • "Benign simple renal cyst requiring no follow up"

Class II

  • "Benign Bosniak II renal cyst requiring no follow up"
  • "Likely benign Bosniak II renal mass requiring no follow up"

Class IIF

  • "Bosniak IIF cystic renal mass. The large majority of Bosniak IIF masses are benign. When malignant, nearly all are indolent. Generally, Bosniak IIF masses are followed at imaging at 6 months and 12 months, then annually for a total of 5 years to assess for morphologic change"

Class III

  • "Bosniak III cystic renal mass. Bosniak III masses have an intermediate probability of being malignant. If not already obtained, consider urology consultation"

Class IV

  • "Bosniak IV cystic renal mass. The large majority of Bosniak IV masses are malignant. If not already obtained, consider urology consultation"
  • the increased specificity about thickness of walls and septa, and number of septa, is intended to increase inter-reader agreement
  • the differentiation between "irregular thickening" (Bosniak III) and "nodule" (Bosniak IV) is intended to reduce the percentage of Bosniak IV masses that are benign
  • this classification scheme is intended for a general patient and not for those with a renal cell carcinoma syndrome

Article information

rID: 86757
System: Urogenital
Synonyms or Alternate Spellings:
  • Bosniak classification, version 2019
  • Bosniak 2019

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