Brain chagoma is a term used to describe brain lesions in immune compromised individuals with Trypanosoma cruzi parasite infection (Chagas disease). These are white matter lesions which may involve the cortex, and have nonspecific appearances which are indistinguishable from other tumoral lesions in immune compromised individuals such as neurotoxoplasmosis and primary CNS lymphoma 1,2.
These are distinct from the cutaneous lesion chagoma, which can occur at the site of the causative Trypanosoma cruzi inoculation.
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