Breast hamartoma
Updates to Article Attributes
Breast hamartoma (also known as a fibroadenolipoma) is a benign breast lesion.
Epidemiology
They typically occur in women older than 35 years of age.
Clinical presentation
While it can present as a painless soft lump, it may also present as unilateral unilateral breast enlargement without a palpable localised mass lesion 4.
Pathology
It results from a benign proliferation of fibrous, glandular, and fatty tissue (hence fibro-adeno-lipoma) surrounded by a thin capsule of connective tissue. All components are found in normal breast tissue (hence the termhamartoma).
Macroscopically, hamartomas are slightly larger and softer than common adenofibromas and, are well-defined, whitish, pinkish and fleshy, with islands of yellow fat tissue. Histologically, they exhibit pushing borders with a pseudo-encapsulation, and consist of a combination of variable amounts of stromal and epithelial components.
Associations
- Cowden syndrome: with multiple hamartomas
Radiographic features
Lesions can be any size but are typically large at presentation.
Mammography
Typically seen as a well-circumscribed, round to oval inhomogeneous mass surrounded by thin capsule, comprising of both fat and soft-tissue densities (both radiolucent and radiodense components). Sometimes this is described as a "breast within a breast" appearance.
Ultrasound
MayBecause it resembles the normal breast tissue usually it is difficult to delineate the margins. It may be seen as a well-circumscribed, solid lesion without any intra any intra lesional microcalcification. Internal echotexture most often is either often mixed with both hyper-echoic or of mixed echogenicityand hypoechoic components 3. Lesions are soft and easy to compress.
History and etymology
It was initially described by M G Arrigoni in 1971 2
-<p><strong>Breast hamartoma</strong> (also known as a <strong>fibroadenolipoma</strong>) is a <a href="/articles/benign-breast-lesion">benign breast lesion</a>.</p><h4>Epidemiology</h4><p>They typically occur in women older than 35 years of age. </p><h4>Clinical presentation</h4><p>While it can present as a painless soft lump, it may also present as unilateral breast enlargement without a palpable localised mass lesion <sup>4</sup>.</p><h4>Pathology</h4><p>It results from a benign proliferation of fibrous, glandular, and fatty tissue (hence fibro-adeno-lipoma) surrounded by a thin capsule of connective tissue. All components are found in normal breast tissue (hence the term <a href="/articles/hamartoma">hamartoma</a>).</p><p>Macroscopically, hamartomas are slightly larger and softer than common adenofibromas and, are well-defined, whitish, pinkish and fleshy, with islands of yellow fat tissue. Histologically, they exhibit pushing borders with a pseudo-encapsulation, and consist of a combination of variable amounts of stromal and epithelial components.</p><h5>Associations</h5><ul><li>-<a href="/articles/cowden-syndrome">Cowden syndrome</a>: with multiple hamartomas</li></ul><h4>Radiographic features</h4><p>Lesions can be any size but are typically large at presentation.</p><h5>Mammography</h5><p>Typically seen as a well-circumscribed, round to oval inhomogeneous mass surrounded by thin capsule, comprising of both fat and soft-tissue densities (both radiolucent and radiodense components). Sometimes this is described as a "<a href="/articles/breast-within-a-breast-sign">breast within a breast</a>" appearance.</p><h5>Ultrasound</h5><p>May be seen as a well-circumscribed, solid lesion without any intra lesional microcalcification. Internal echotexture most often is either hyper-echoic or of mixed echogenicity <sup>3</sup>.</p><h4>History and etymology</h4><p>It was initially described by <strong>M G Arrigoni </strong>in 1971 <sup>2</sup></p>- +<p><strong>Breast hamartoma</strong> (also known as a <strong>fibroadenolipoma</strong>) is a <a href="/articles/benign-breast-lesion">benign breast lesion</a>.</p><h4>Epidemiology</h4><p>They typically occur in women older than 35 years of age. </p><h4>Clinical presentation</h4><p>While it can present as a painless soft lump, it may also present as unilateral breast enlargement without a palpable localised mass lesion <sup>4</sup>.</p><h4>Pathology</h4><p>It results from a benign proliferation of fibrous, glandular, and fatty tissue (hence fibro-adeno-lipoma) surrounded by a thin capsule of connective tissue. All components are found in normal breast tissue (hence the term <a href="/articles/hamartoma">hamartoma</a>).</p><p>Macroscopically, hamartomas are slightly larger and softer than common adenofibromas and, are well-defined, whitish, pinkish and fleshy, with islands of yellow fat tissue. Histologically, they exhibit pushing borders with a pseudo-encapsulation, and consist of a combination of variable amounts of stromal and epithelial components.</p><h5>Associations</h5><ul><li>
- +<a href="/articles/cowden-syndrome">Cowden syndrome</a>: with multiple hamartomas</li></ul><h4>Radiographic features</h4><p>Lesions can be any size but are typically large at presentation.</p><h5>Mammography</h5><p>Typically seen as a well-circumscribed, round to oval inhomogeneous mass surrounded by thin capsule, comprising of both fat and soft-tissue densities (both radiolucent and radiodense components). Sometimes this is described as a "<a href="/articles/breast-within-a-breast-sign">breast within a breast</a>" appearance.</p><h5>Ultrasound</h5><p>Because it resembles the normal breast tissue usually it is difficult to delineate the margins. It may be seen as a well-circumscribed, solid lesion without any intra lesional microcalcification. Internal echotexture most often mixed with both hyper-echoic and hypoechoic components <sup>3</sup>. Lesions are soft and easy to compress.</p><h4>History and etymology</h4><p>It was initially described by <strong>M G Arrigoni </strong>in 1971 <sup>2</sup></p>
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