Chagoma describes a cutaneous erythematous reactive lesion at the insect bite inoculation site of Trypanosoma cruzi parasite (causative agent in Chagas disease) 1-3. The lesion appears in the weeks after infection and may then persist for several weeks 1,2.
Brain chagoma is a distinct entity referring to CNS lesions associated with Chagas disease in immunocompromised individuals 4.