Citation, DOI, disclosures and article data
Citation:
Gaillard F, Sharma R, Mahsoub M, et al. Classification system for malformations of the cerebellum. Reference article, Radiopaedia.org (Accessed on 22 Feb 2025) https://doi.org/10.53347/rID-15854
Classification systems for malformations of the cerebellum are varied and are constantly being revised as a greater understanding of the underlying genetics and embryology of the disorders is uncovered.
Classification
A classification proposed by Barkovich et al. in 2009 1 divides cerebellar malformations into two broad groups: those with cerebellar hypoplasia and those with cerebellar dysplasia.
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cerebellar hypoplasia: reduced cerebellar volume 2
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focal hypoplasia
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generalized hypoplasia
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cerebellar dysplasia: abnormal cerebellar foliation, fissuration, and architecture of the cerebellar white matter 2
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focal dysplasia
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generalized dysplasia
congenital muscular dystrophies
cytomegalovirus
lissencephaly with RELN mutation
lissencephaly with agenesis of corpus callosum and cerebellar dysplasia
associated with diffuse cerebral polymicrogyria
diffusely abnormal foliation
Poretti-Boltshauser syndrome
See also
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1. Barkovich A, Millen K, Dobyns W. A Developmental and Genetic Classification for Midbrain-Hindbrain Malformations. Brain. 2009;132(Pt 12):3199-230. doi:10.1093/brain/awp247 - Pubmed
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2. Bosemani T, Orman G, Boltshauser E, Tekes A, Huisman T, Poretti A. Congenital Abnormalities of the Posterior Fossa. Radiographics. 2015;35(1):200-20. doi:10.1148/rg.351140038 - Pubmed
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3. Patel S & Barkovich A. Analysis and Classification of Cerebellar Malformations. AJNR Am J Neuroradiol. 2002;23(7):1074-87. PMC8185716 - Pubmed
Multiple choice questions:
Related articles: Malformations of the central nervous system
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malformations of cortical development
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- abnormal brain size
- abnormal cell proliferation
- non-neoplastic
- neoplastic
- abnormal neuronal migration
- lissencephaly
- heterotopia: ectopic migration
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- not otherwise classified
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midline abnormalities of the brain
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malformations of the cerebellum
- cerebellar hypoplasia
- focal hypoplasia
- generalized hypoplasia
- with enlarged fourth ventricle
- normal fourth ventricle
- with normal pons
- with small pons
- cerebellar dysplasia
- focal dysplasia
- isolated vermian dysplasia
- isolated hemispheric dysplasia
- generalized dysplasia
- congenital muscular dystrophies
- cytomegalovirus
- lissencephaly with RELN mutation
- lissencephaly with agenesis of corpus callosum and cerebellar dysplasia
- associated with diffuse cerebral polymicrogyria
- diffusely abnormal foliation
- malformations of the brainstem
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