Question 1207
{"accessible":false,"alternatives":[{"id":6045,"text":"adrenocorticotropic hormone (ACTH) is secreted in response to corticotropin-releasing hormone (CRH)"},{"id":6046,"text":"follicle-stimulating hormone (FSH) and Luteinizing hormone (LH) secretion is controlled by gonadotropin-releasing hormone (GnRH)"},{"id":6047,"text":"growth hormone (GH) is controlled by GH releasing hormone and GH inhibitory hormone (somatostatin)"},{"id":6048,"text":"thyroid stimulating hormone (TSH) is secreted in response to thyrotropin-releasing hormone (TRH)thyroid-stimulating"},{"id":6049,"text":"prolactin (PRL) is secreted in response to PRL releasing hormone (dopamine)"}],"archived":false,"correctAlternativeId":6049,"explanation":"\u003cp\u003eExcept during pregnancy, when prolactin is secreted in response to prolactin-releasing hormone, prolactin is tonically inhibited by prolactin inhibitory hormone (PIH) also known as dopamine. This accounts for modest elevation when dopamine antagonists (e.g. neuroleptics) are used or when the stalk it compressed or interrupted. It also explains why prolactinomas respond to medical therapy with dopamine agonists (e.g. cabergoline).\u0026nbsp;\u003c/p\u003e","id":1207,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/2989","nextQuestionPath":"/articles/elevated-prolactin-differential/questions/850","relatedArticles":[],"alsoUsedIn":[{"id":432,"kind":"Course","title":"Radiology Review Course - Melbourne - page 432","link":"https://radiopaedia.org/courses/radiology-review-course-melbourne-2019/pages/432"},{"id":432,"kind":"Course","title":"Radiology Review Course - Melbourne - page 432","link":"https://radiopaedia.org/courses/radiology-review-course-melbourne-2020/pages/432"},{"id":432,"kind":"Course","title":"Radiology Review Course - page 432","link":"https://radiopaedia.org/courses/radiology-review-course-online/pages/432"},{"id":462,"kind":"RestrictedPage","title":"Page 462 (in no courses)","link":"https://radiopaedia.org/admin/restricted_pages/462"},{"id":463,"kind":"RestrictedPage","title":"Page 463 (in no courses)","link":"https://radiopaedia.org/admin/restricted_pages/463"},{"id":589,"kind":"Course","title":"Radiology lectures for ENT Trainees - page 589","link":"https://radiopaedia.org/courses/radiology-lectures-for-ent-trainees/pages/589"},{"id":619,"kind":"Course","title":"Neuroradiology Lectures - page 619","link":"https://radiopaedia.org/courses/neuroradiology-lectures/pages/619"},{"id":619,"kind":"Course","title":"Radiopaedia 2020 - Lectures Only - page 619","link":"https://radiopaedia.org/courses/radiopaedia-2020-exclusive/pages/619"},{"id":619,"kind":"Course","title":"2020 Virtual Conference Private Use - page 619","link":"https://radiopaedia.org/courses/2020-virtual-conference-private-use/pages/619"},{"id":619,"kind":"Course","title":"New test course - page 619","link":"https://radiopaedia.org/courses/new-test-course/pages/619"}],"stem":"\u003cp\u003eWhich of the following is\u0026nbsp;\u003cstrong\u003eFALSE\u003c/strong\u003e\u0026nbsp;regarding the normal hormonal control of anterior pituitary hormones?\u0026nbsp;\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/1207"}],"attemptsPercentages":[{"alternativeId":"6049","percentage":82},{"alternativeId":"6048","percentage":5},{"alternativeId":"6047","percentage":6},{"alternativeId":"6046","percentage":3},{"alternativeId":"6045","percentage":5}],"promptToLogin":false,"questionManager":false,"articleId":"elevated-prolactin-differential"}