Functional gastrointestinal disorders

Last revised by Daniel J Bell on 17 Feb 2020

The functional gastrointestinal disorders (FGIDs) are a set of conditions characterized by their chronic GI manifestations, in the absence of structural abnormality of the gut. These conditions are common and may be disabling in nature. The understanding of their pathogenesis is incomplete, complex and linked to dysfunctioning of the gut-brain axis, the gut microbiome and/or immune system.

The spectrum of described disorders is very broad and includes:

The functional gastrointestinal disorders form part of the wider spectrum of functional somatic syndromes, which includes poorly-understood conditions like fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome.

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