Weerakkody Y, Silverstone L, Knipe H, et al. Pulmonary fungal disease. Reference article, Radiopaedia.org (Accessed on 04 May 2024) https://doi.org/10.53347/rID-32147
Pulmonary fungal disease is caused by various organisms of varying virulence and varying sensitivity to antifungal drugs. Immunocompromise, particularly neutropaenia is a major risk factor for invasive and disseminated disease.
Pathologic fungi include:
pulmonary aspergillosis: pulmonary aspergillus infection considered the most important in immunocompromised individuals 5
aspergilloma (saprophytic/non-invasive aspergillosis): the most common form seen radiographically
2. Oh YW, Effmann EL, Godwin JD. Pulmonary infections in immunocompromised hosts: the importance of correlating the conventional radiologic appearance with the clinical setting. Radiology. 2000;217 (3): 647-56. doi:10.1148/radiology.217.3.r00dc35647 - Pubmed citation
3. Mori M, Galvin JR, Barloon TJ et-al. Fungal pulmonary infections after bone marrow transplantation: evaluation with radiography and CT. Radiology. 1991;178 (3): 721-6. doi:10.1148/radiology.178.3.1994408 - Pubmed citation
4. Walker CM, Abbott GF, Greene RE et-al. Imaging pulmonary infection: classic signs and patterns. AJR Am J Roentgenol. 2014;202 (3): 479-92. doi:10.2214/AJR.13.11463 - Pubmed citation
5. Barnes RA. Early diagnosis of fungal infection in immunocompromised patients. J. Antimicrob. Chemother. 2008;61 Suppl 1 (Supplement 1): i3-6. doi:10.1093/jac/dkm424 - Pubmed citation
6. Orlowski HLP, McWilliams S, Mellnick VM, Bhalla S, Lubner MG, Pickhardt PJ, Menias CO. Imaging Spectrum of Invasive Fungal and Fungal-like Infections. (2017) Radiographics : a review publication of the Radiological Society of North America, Inc. 37 (4): 1119-1134. doi:10.1148/rg.2017160110 - Pubmed
7. Ahmad Sarji S, Wan Abdullah W, Wastie M. Imaging features of fungal infection in immuno-suppressed patients in a local ward outbreak. (2006) Biomedical imaging and intervention journal. 2 (2): e21. doi:10.2349/biij.2.2.e21 - Pubmed
8. Christe A, Lin MC, Yen AC, Hallett RL, Roychoudhury K, Schmitzberger F, Fleischmann D, Leung AN, Rubin GD, Rubin GD, Vock P, Roos JE. CT patterns of fungal pulmonary infections of the lung: comparison of standard-dose and simulated low-dose CT. (2012) European journal of radiology. 81 (10): 2860-6. doi:10.1016/j.ejrad.2011.06.059 - Pubmed
9. Presterl E, Parschalk B, Bauer E, Lassnigg A, Hajdu S, Graninger W. Invasive fungal infections and (1,3)-beta-D-glucan serum concentrations in long-term intensive care patients. (2009) International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 13 (6): 707-12. doi:10.1016/j.ijid.2008.10.013 - Pubmed
10. Alexander B, Lamoth F, Heussel C et al. Guidance on Imaging for Invasive Pulmonary Aspergillosis and Mucormycosis: From the Imaging Working Group for the Revision and Update of the Consensus Definitions of Fungal Disease from the EORTC/MSGERC. Clin Infect Dis. 2021;72(Suppl 2):S79-88. doi:10.1093/cid/ciaa1855 - Pubmed
11. Konsoula A, Tsioutis C, Markaki I, Papadakis M, Agouridis A, Spernovasilis N. Lomentospora Prolificans: An Emerging Opportunistic Fungal Pathogen. Microorganisms. 2022;10(7):1317. doi:10.3390/microorganisms10071317 - Pubmed