Lipoblastoma is a rare, benign, encapsulated tumour arising from embryonic white fat.
It occurs primarily in infancy and early childhood (more than 90% before age 3). It most often occurs in the extremities and trunk, although it can be seen in other areas 1. The entity was originally described as an infiltrating anterior chest wall mass.
Imaging features are non-specific. Lipoblastomas is classically a predominantly fatty mass with well-defined margins. However, it may have myxoid components that predominate and that can also be enhancing.
Lipoblastomas can look very much like a liposarcoma, but liposarcoma is extremely rare in children (0.08% occur below age 10) 2.
Treatment and prognosis
Lipoblastomas have traditionally been treated with excision, although this practice has been called into question. There is a recurrence rate of up to 20% with no recorded case of metastasis. Some cases have matured into lipomas.3
- 1. Kok KY, Telisinghe PU. Lipoblastoma: clinical features, treatment, and outcome. World J Surg. 2010;34 (7): 1517-22. doi:10.1007/s00268-010-0466-8 - Pubmed citation
- 2. Kransdorf MJ, Murphey MD. Imaging of Soft Tissue Tumors. Lippincott Williams & Wilkins. (2006) ISBN:0781747716. Read it at Google Books - Find it at Amazon
- 3. Moholkar S, Sebire NJ, Roebuck DJ. Radiological-pathological correlation in lipoblastoma and lipoblastomatosis. Pediatr Radiol. 2006;36 (8): 851-6. doi:10.1007/s00247-006-0175-5 - Pubmed citation