Malignant fibrous histiocytoma of the retroperitoneum

Retroperitoneal malignant fibrous histiocytomas are an uncommon tumour overall but are considered as one of the most common types of primary retroperitoneal neoplasms

For a broad discussion of this type of tumour, which commonly involves the extremities, please refer to the main article on malignant fibrous histiocytoma (MFH).

Retroperitoneal malignant fibrous histiocytomas correspond to approximately 15% of all MFHs 3

They occur with predominance in men.

They are categorised as sarcomas and are often high-grade tumours. 

There are six histological subtypes: storiform, pleomorphic, myxoid, giant cell, inflammatory and angiomatoid. Most metastasize and common sites include lung and lymph nodes.

Imaging is not characteristic and clarification pathologically is required. Reassessment of malignant fibrous histiocytoma diagnosis in some series result in re-classification as dedifferentiated liposarcomas.

25% of cases include dystrophic calcification which is uncommon amongst the remaining primary retroperitoneal malignancies.

Share article

Article information

rID: 6338
Synonyms or Alternate Spellings:
  • Malignant fibrous histiocytoma of the retroperitoneum
  • Malignant fibrous histiocytoma: retroperitoneum
  • Retroperitoneal malignant fibrous histiocytomas

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.