Malignant phyllodes tumor
Updates to Article Attributes
Malignant phyllodes tumours of the breast account a small proportion (5-25% 2) of phyllodes tumours.
Pathology
It is generally thought that it is the stromal component that becomes malignant 4. This may account for their haematogenous metastatic pattern.
Radiographic features
General
A substantial overlap in the imaging characteristics have been reported between benign and malignant phyllodes tumours. A tumour diameter of 3 cm or greater has been generally reported to be associated with a higher likelihood of malignancy 3.
Treatment and prognosis
Fewer than 20% of the malignant tumors metastasise. When metastatic disease does occur, the metastases usually spread haematogenously to the lungs, pleura, or bone. Surgery is mainstay of treatment as they are not proven to be sensitive to radio- or chemotherapy.
See also
-<p><strong>Malignant phyllodes tumours of the breast </strong>account a small proportion (5-25% <sup>2</sup>) of <a href="/articles/phyllodes-tumour">phyllodes tumours</a>.</p><h4>Pathology</h4><p>It is generally thought that it is the stromal component that becomes malignant <sup>4</sup>. This may account for their haematogenous metastatic pattern.</p><h4>Radiographic features</h4><h5>General</h5><p>A substantial overlap in the imaging characteristics have been reported between benign and malignant phyllodes tumours. A tumour diameter of 3 cm or greater has been generally reported to be associated with a higher likelihood of malignancy <sup>3</sup>.</p><h4>Treatment and prognosis</h4><p>Fewer than 20% of the malignant tumors metastasise. When metastatic disease does occur, the metastases usually spread haematogenously to the lungs, pleura, or bone. Surgery is mainstay of treatment as they are not proven to be sensitive to radio- or chemotherapy.</p><h4>See also</h4><ul>-<li><a href="/articles/breast-neoplasms">breast neoplasms</a></li>-<li><a href="/articles/sarcoma-of-breast">breast sarcomas</a></li>-</ul>- +<p><strong>Malignant phyllodes tumours of the breast </strong>account a small proportion (5-25% <sup>2</sup>) of <a href="/articles/phyllodes-tumour">phyllodes tumours</a>.</p><h4>Pathology</h4><p>It is generally thought that it is the stromal component that becomes malignant <sup>4</sup>. This may account for their haematogenous metastatic pattern.</p><h4>Radiographic features</h4><p>A substantial overlap in the imaging characteristics have been reported between benign and malignant phyllodes tumours. A tumour diameter of 3 cm or greater has been generally reported to be associated with a higher likelihood of malignancy <sup>3</sup>.</p><h4>Treatment and prognosis</h4><p>Fewer than 20% of the malignant tumors metastasise. When metastatic disease does occur, the metastases usually spread haematogenously to the lungs, pleura, or bone. Surgery is mainstay of treatment as they are not proven to be sensitive to radio- or chemotherapy.</p>