Mammary myofibroblastoma
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MyofibroblastomaMammary myofibroblastoma is a rare, benign, circumscribed mesenchymal breast tumour.
Epidemiology
It is the only breast tumour that occurs more commonly in males than females 2. It also has a tendency to occur more often in elderly males and postmenopausal women.
Pathology
It arises from the stromal spindle cells of the breast 1. It stains positive for immunoreactive markers for desmin, smooth muscle, and actin.
Radiographic features
Mammography
- circumscribed mass
- no calcifications
- greatest diameter no more than 1-4 cm
Ultrasound
It usually has the appearance of a fibroadenoma:
- circumscribed homogenous
- slightly hypoechoic
MRI
- circumscribed mass
- internal septations
- homogenous enhancement
Treatment
and prognosisComplete resection is recommended as it has a high rate of recurrence if not completely excised 3.
Differential Diagnosis
diagnosis
-<p><strong>Myofibroblastoma</strong> is a rare, benign, circumscribed mesenchymal <a title="Breast tumour" href="/articles/breast-neoplasms">breast tumour</a>. </p><h4>Epidemiology</h4><p>It is the only breast tumour that occurs more commonly in males than females <sup>2</sup>. It also has a tendency to occur more in elderly males and postmenopausal women.</p><h4>Pathology</h4><p>It arises from the stromal spindle cells of the breast <sup>1</sup>. It stains positive for immunoreactive markers for desmin, smooth muscle, and actin.</p><h4>Radiographic features</h4><h5>Mammography</h5><ul>- +<p><strong>Mammary myofibroblastoma</strong> is a rare, benign, circumscribed mesenchymal <a href="/articles/breast-neoplasms">breast tumour</a>. </p><h4>Epidemiology</h4><p>It is the only breast tumour that occurs more commonly in males than females <sup>2</sup>. It also has a tendency to occur more often in elderly males and postmenopausal women.</p><h4>Pathology</h4><p>It arises from the stromal spindle cells of the breast <sup>1</sup>. It stains positive for immunoreactive markers for desmin, smooth muscle, and actin.</p><h4>Radiographic features</h4><h5>Mammography</h5><ul>
-</ul><h5>Treatment</h5><p>Complete resection is recommended as it has a high rate of recurrence if not completely excised <sup>3</sup>.</p><h5>Differential Diagnosis</h5><ul>-<li><a title="Fibroadenoma (breast)" href="/articles/fibroadenoma-breast">fibroadenoma</a></li>-<li><a title="Hamartoma of breast" href="/articles/breast-hamartoma">hamartoma</a></li>-<li><a title="Lipoma of breast" href="/articles/breast-lipoma">lipoma</a></li>- +</ul><h4>Treatment and prognosis</h4><p>Complete resection is recommended as it has a high rate of recurrence if not completely excised <sup>3</sup>.</p><h4>Differential diagnosis</h4><ul>
- +<li><a href="/articles/fibroadenoma-breast">fibroadenoma</a></li>
- +<li><a href="/articles/breast-hamartoma">hamartoma</a></li>
- +<li><a href="/articles/breast-lipoma">lipoma</a></li>
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