Modic type endplate changes

Changed by Craig Hacking, 26 Jan 2023
Disclosures - updated 30 Aug 2022:
  • Philips Australia, Paid speaker at Philips Spectral CT events (ongoing)

Updates to Article Attributes

Body was changed:

Modic type endplate changes represent a classification for vertebral body endplate MRI signal changes, first described in 1988 1. It is widely recognised by radiologists and clinicians and is a useful shorthand for reporting MRIs of the spine.

Recently Modic type I has received renewed attention due to the possibility of it representing low-grade indolent infection. It is thus discussed separately here.

  • Modic type I:

    • T1: low signal
    • T2: high signal
    • represents bone marrow oedema and inflammation
      • T1: low signal

      • T2: high signal

      • T1 C+ (Gd): enhancement

    • Modic type II:

      • T1: high signal
      • T2: iso to high signal
      • represents normal red haemopoietic bone marrow conversioninto yellow fatty marrowas a result of marrow ischaemia
        • T1: high signal

        • T2: iso to high signal

      • Modic type III:

        • T1: low signal
        • T2: low signal
        • representssubchondral bony sclerosis
          • T1: low signal

          • T2: low signal

        History and etymology

        Michael T Modic (fl. 2018) is an American neuroradiologist at the Vanderbilt University Medical Centre in Nashville, Tennessee, in the US, although almost the whole of his career prior to 2018 was spent at the Cleveland Clinic 3.

  • -<p><strong>Modic type endplate changes</strong> represent a classification for vertebral body <a href="/articles/vertebral-body-endplate">endplate</a> MRI signal, first described in 1988 <sup>1</sup>. It is widely recognised by radiologists and clinicians and is a useful shorthand for reporting MRIs of the spine.</p><p>Recently <a href="/articles/modic-type-i-endplate-change">Modic type I</a> has received renewed attention due to the possibility of it representing low-grade indolent infection. It is thus discussed separately <a href="/articles/modic-type-i-endplate-change">here</a>.</p><ul>
  • +<p><strong>Modic type endplate changes</strong> represent a classification for vertebral body <a href="/articles/vertebral-body-endplate">endplate</a> MRI signal changes, first described in 1988 <sup>1</sup>. It is widely recognised by radiologists and clinicians and is a useful shorthand for reporting MRIs of the spine.</p><p>Recently <a href="/articles/modic-type-i-endplate-change">Modic type I</a> has received renewed attention due to the possibility of it representing low-grade indolent infection. It is thus discussed separately <a href="/articles/modic-type-i-endplate-change">here</a>.</p><ul>
  • -<strong>Modic type I</strong><ul>
  • -<li>
  • -<strong>T1:</strong> low signal</li>
  • -<li>
  • -<strong>T2:</strong> high signal</li>
  • -<li>represents bone marrow oedema and inflammation</li>
  • -<li>
  • -<strong>T1 C+ (Gd):</strong> enhancement</li>
  • +<p><strong>Modic type I: </strong>represents bone marrow oedema and inflammation</p>
  • +<ul>
  • +<li><p><strong>T1:</strong> low signal</p></li>
  • +<li><p><strong>T2:</strong> high signal</p></li>
  • +<li><p><strong>T1 C+ (Gd):</strong> enhancement</p></li>
  • -<strong>Modic type II</strong><ul>
  • -<li>
  • -<strong>T1:</strong> high signal</li>
  • -<li>
  • -<strong>T2:</strong> iso to high signal</li>
  • -<li>represents normal red haemopoietic bone marrow conversion<sup> </sup>into yellow fatty marrow<sup> </sup>as a result of marrow ischaemia</li>
  • +<p><strong>Modic type II: </strong>represents normal red haemopoietic bone marrow conversion<sup> </sup>into yellow fatty marrow<sup> </sup>as a result of marrow ischaemia</p>
  • +<ul>
  • +<li><p><strong>T1:</strong> high signal</p></li>
  • +<li><p><strong>T2:</strong> iso to high signal</p></li>
  • -<strong>Modic type III</strong><ul>
  • -<li>
  • -<strong>T1:</strong> low signal</li>
  • -<li>
  • -<strong>T2:</strong> low signal</li>
  • -<li>represents<sup> </sup>subchondral bony sclerosis</li>
  • +<p><strong>Modic type III: </strong>represents<sup> </sup>subchondral bony sclerosis</p>
  • +<ul>
  • +<li><p><strong>T1:</strong> low signal</p></li>
  • +<li><p><strong>T2:</strong> low signal</p></li>

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