Myxoid degeneration of a leiomyoma
While this type of degeneration is generally considered rare. The higher end of prevalence for this type of degeneration has been reported up to 50% of all degenerations 5.
Fibroids that have undergone myxoid degeneration are filled with a gelatinous material and can be difficult to differentiate from fibroids that have undergone cystic degeneration; however, they typically appear as more complex cystic masses.
On pelvic MRI, the myxoid material usually demonstrates 2:
- T1 - low signal intensity
- T2 - very high signal intensity 2-3
- T1 C+ (Gd) - there is minimal or no enhancement 2-3
The above signal changes are present as intralesional change 4 amongst the background low T2 signal of non-myxoid components.
Certain malignant uterine tumours also contain myxoid degeneration and include:
- 1. Wilde S, Scott-barrett S. Radiological appearances of uterine fibroids. Indian J Radiol Imaging. 19 (3): 222-31. doi:10.4103/0971-3026.54887 - Free text at pubmed - Pubmed citation
- 2. Murase E, Siegelman ES, Outwater EK et-al. Uterine leiomyomas: histopathologic features, MR imaging findings, differential diagnosis, and treatment. Radiographics. 19 (5): 1179-97. Radiographics (full text) - Pubmed citation
- 3. Ueda H, Togashi K, Konishi I et-al. Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds. Radiographics. 1999;19 Spec No : S131-45. Radiographics (full text) - Pubmed citation
- 4. Hamm B, Baert AL, Beinder E( et-al. MRI and CT of the Female Pelvis. Springer Verlag. (2010) ISBN:3642060897. Read it at Google Books - Find it at Amazon
- 5. Dähnert W. Radiology Review Manual. Lippincott Williams & Wilkins. (2011) ISBN:1609139437. Read it at Google Books - Find it at Amazon