Neu-Laxova syndrome

Neu-Laxova syndrome is a lethal autosomal recessive multiple malformation syndrome with a heterogeneous phenotype.

The clinical spectrum can be quite wide and includes:

Antenatal ultrasound

May show a combination of any of the clinical features to varying degrees.

The combination of marked ocular proptosis in a growth restricted, oedematous fetus could prompt consideration 1 although individual features nonspecific.

The prognosis is very poor with most fetuses undergoing intrauterine death and the remainder not surviving the early neonatal period.

Share article

Article Information

rID: 12371
Section: Syndromes
Synonyms or Alternate Spellings:
  • Neu-Laxova syndrome (NLS)
  • Neu Laxova syndrome

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.