Ossification vs calcification

In discussing mineralization, many radiology textbooks use the term calcification and make no mention of ossification.

  • ossification - 
    • is a process of laying down new bone material. It is synonymous with bone tissue formation. 
    • bone may form in any region where there are fibroblasts, excess of calcium and an adequate blood-supply.
  • calcification -
    • is the process in which calcium salts build up in soft tissue, causing it to harden. 
    • calcifications may be classified on whether there is mineral balance or not, and the location of the calcification
    • pathological calcification is observed in any mesenchymatous tissue of low metabolism when the vascularity is further reduced by the fibrosis of trauma or of infection.
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Article information

rID: 21816
Tag: cases
Synonyms or Alternate Spellings:
  • Distinction between calcification and ossification

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