Papillary-predominant adenocarcinoma of the lung

Changed by Bruno Di Muzio, 11 Aug 2018

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Papillary predominant adenocarcinoma of the lung
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Papillary predominant adenocarcinoma of the lung is a subtype of adenocarcinoma of the lung.

Epidemiology

It may account for 7-12% of all lung adenocarcinomas. There may be predilection in female non smokers-smokers 1.

Pathology

It this form papillary structures replace the underlying alveolar architecture. True papillary adenocarcinoma is usually diagnosed when the pathological features constitute >75% of the tumour on histopathology.

Radiographic features

CT 

Variable appearances have been described randingranging from a solitary pulmonary nodule, as a mass containing internal bubble lucencies with surrounding ground-glass opacity and satellite micronodules or as a triangular mass with satellite micronodules 2.

Treatment and prognosis

The presence of a micropapillary component in papillary carcinoma has been associated with early lymph node metastasis, intrapulmonary metastasis and a significantly lower 5-year survival rate 1.

  • -<p><strong>Papillary predominant adenocarcinoma of lung</strong> is a subtype of <a href="/articles/adenocarcinoma-of-the-lung">adenocarcinoma of the lung</a>.</p><h4>Epidemiology</h4><p>It may account for 7-12% of all lung adenocarcinomas. There may be predilection in female non smokers<sup> 1</sup>.</p><h4>Pathology</h4><p>It this form papillary structures replace the underlying alveolar architecture. True papillary adenocarcinoma is usually diagnosed when the pathological features constitute &gt;75% of the tumour on histopathology.</p><h4>Radiographic features</h4><h5>CT </h5><p>Variable appearances have been described randing from a solitary pulmonary nodule, as a mass containing internal bubble lucencies with surrounding ground-glass opacity and satellite micronodules or as a triangular mass with satellite micronodules <sup>2</sup>.</p><h4>Treatment and prognosis</h4><p>The presence of micropapillary component in papillary carcinoma has been associated with early lymph node metastasis, intrapulmonary metastasis and a significantly lower 5-year survival rate<sup> 1</sup>.</p>
  • +<p><strong>Papillary predominant adenocarcinoma of the lung</strong> is a subtype of <a href="/articles/adenocarcinoma-of-the-lung">adenocarcinoma of the lung</a>.</p><h4>Epidemiology</h4><p>It may account for 7-12% of all lung adenocarcinomas. There may be predilection in female non-smokers<sup> 1</sup>.</p><h4>Pathology</h4><p>It this form papillary structures replace the underlying alveolar architecture. True papillary adenocarcinoma is usually diagnosed when the pathological features constitute &gt;75% of the tumour on histopathology.</p><h4>Radiographic features</h4><h5>CT </h5><p>Variable appearances have been described ranging from a solitary pulmonary nodule, as a mass containing internal bubble lucencies with surrounding ground-glass opacity and satellite micronodules or as a triangular mass with satellite micronodules <sup>2</sup>.</p><h4>Treatment and prognosis</h4><p>The presence of a micropapillary component in papillary carcinoma has been associated with early lymph node metastasis, intrapulmonary metastasis and a significantly lower 5-year survival rate<sup> 1</sup>.</p>
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Image 1 CT (lung window) ( create )

Image 2 Nuclear medicine (18FDG PET-CT) ( create )

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Papillary predominant adenocarcinoma of lung
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