Reactive arthritis
Updates to Article Attributes
Reactive arthritis (formerly known as Reiter disease) is a sterile inflammatory arthritis that follows an infection at a different site, commonly enteric or urogenital. It is classified as type of seronegative spondyloarthropathy.
Epidemiology
It favours males between age 15-35 and occurs after an infective illness 2.
Pathology
In reactive arthritis there is joint inflammation, bone proliferation, periostitis, and enthesitis.
HLA B27 is positive in approximately 80% of patients.
Clinical presentation
Usually transient following infection and involving one or two large joints. Because common systems involved include
The following mnemonic can be used to remember the eye, the urinary system, and the feet, one clinical mnemonic for Reiter's syndrome is classic triad encountered in Reactive Arthritis: "Can't see, can't pee, can't climb a tree''.
Classic triad:
- arthritis
- conjunctivitis
- urethritis
Radiographic features
Distal lower-extremity involvement (MTP>>calcaneus>ankle>knee) is more common than upper-extremity involvement; It affects hands, wrists, and feet with a distribution that is unilateral or bilateral and asymmetric (it becomes symmetric in late stage).
It can have a very similar appearance to psoriatic arthritis with the classic features of ill-defined erosions, enthesopathy, bone proliferation, early juxta-articular osteoporosis, uniform joint space loss and fusiform soft tissue swelling 2. However, the distribution is slightly different. Where hand involvement is the most common site in patient's with psoriatic arthritis, hand involvement with Reactive Arthritis is very uncommon 2.
Both Psoriasis and Reactive Arthritis can cause a sacroiliitis (which is usually asymmetric) 3.
History and etymology
The disease was originally named after Hans Reiter. However, recently this term has not been encouraged as he was a convicted Nazi war criminal who performed experiments of a new typhus vaccine that caused the death of hundreds of prisoners of war.
See also
-<p><strong>Reactive arthritis</strong> (formerly known as <strong>Reiter disease</strong>) is a sterile inflammatory arthritis that follows an infection at a different site, commonly enteric or urogenital. It is classified as type of <a href="/articles/seronegative-spondyloarthritides">seronegative spondyloarthropathy</a>.</p><h4>Epidemiology</h4><p>It favours males between age 15-35 and occurs after an infective illness <sup>2</sup>.</p><h4>Pathology</h4><p>In reactive arthritis there is joint inflammation, bone proliferation, periostitis, and enthesitis.</p><p>HLA B27 is positive in approximately 80% of patients.</p><h4>Clinical presentation</h4><p>Usually transient following infection and involving one or two large joints. Because common systems involved include the eye, the urinary system, and the feet, one clinical mnemonic for Reiter's syndrome is "Can't see, can't pee, can't climb a tree''.</p><p>Classic triad:</p><ul>- +<p><strong>Reactive arthritis</strong> (formerly known as <strong>Reiter disease</strong>) is a sterile inflammatory arthritis that follows an infection at a different site, commonly enteric or urogenital. It is classified as type of <a href="/articles/seronegative-spondyloarthritides">seronegative spondyloarthropathy</a>.</p><h4>Epidemiology</h4><p>It favours males between age 15-35 and occurs after an infective illness <sup>2</sup>.</p><h4>Pathology</h4><p>In reactive arthritis there is joint inflammation, bone proliferation, periostitis, and enthesitis.</p><p>HLA B27 is positive in approximately 80% of patients.</p><h4>Clinical presentation</h4><p>Usually transient following infection and involving one or two large joints. </p><p>The following mnemonic can be used to remember the classic triad encountered in Reactive Arthritis: "Can't see, can't pee, can't climb a tree''.</p><p>Classic triad:</p><ul>
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