Articles

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16,905 results found
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CNS cryptococcosis

CNS cryptococcosis results from infection of the central nervous system with the yeast-like fungus Cryptococcus neoformans. It is the most common fungal infection and second most common opportunistic infection of the central nervous system. For a general discussion of infection with this organi...
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Central nervous system vasculitis

Central nervous system (CNS) vasculitides represent a heterogeneous group of inflammatory diseases (vasculitis or cerebral angiitis) affecting the walls of blood vessels in the brain, spinal cord, and meninges. Please refer to the article on vasculitis for a general discussion of that entity.  ...
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Coal workers' pneumoconiosis

Coal workers' pneumoconiosis (CWP) is an occupational disease (type of pneumoconiosis) caused by exposure to coal dust free of silica (washed coal). Histologically, coal workers' pneumoconiosis is classified according to disease severity into simple (presence of coal macules) and complicated (wi...
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Anterior resection of the rectum

Anterior resection is a surgical procedure to resect the rectum and sigmoid colon while preserving the anal sphincter complex. Indications cancer of the rectum (most common) severe diverticular disease Procedure Most anterior resections are performed laparoscopically, although historically,...
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Hepatic encephalopathy

Hepatic encephalopathy, also known as acute hyperammonemic encephalopathy or portosystemic encephalopathy, refers to a spectrum of neuropsychiatric abnormalities occurring in patients with liver dysfunction and portal hypertension. It results from exposure of the brain to excessive amounts of am...
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Lobar nephronia

Lobar nephronia, also known as acute focal nephritis, refers to an intermediate stage between acute pyelonephritis and renal abscess, and is a focal region of interstitial nephritis.  It appears as a wedge of poorly perfused renal parenchyma, without a cortical rim sign. The condition is discu...
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Osteoporosis

Osteoporosis is a metabolic bone disease characterized by decreased bone mass and skeletal fragility. The World Health Organization (WHO) operationally defines osteoporosis as a bone mineral density T-score less than -2.5 SD (more than 2.5 standard deviations under the young-adult mean), which ...
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Idiopathic myointintimal hyperplasia of the mesenteric veins

Idiopathic myointintimal hyperplasia of the mesenteric veins (IMHMV) is a rare cause of chronic progressive colonic ischemia due to non-thrombotic venous occlusion. Patients are typically misdiagnosed as inflammatory bowel disease or infectious colitis 4. Epidemiology This little known disease...
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Multiple myeloma

Multiple myeloma (MM), also known as plasma cell myeloma, is a multifocal proliferation of plasma cells based in the bone marrow. It is the most common primary malignant bone neoplasm in adults. It arises from red marrow due to the monoclonal proliferation of plasma cells and manifests in a wide...
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Plasmacytoma

Plasmacytomas are discrete, solitary tumors of neoplastic monoclonal plasma cells in either bone or soft tissue (extramedullary). It is a rare tumor that is associated with latent systemic disease in the majority of affected patients. In contradistinction to multiple myeloma, there is minimal or...
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Anomalous course of coronary arteries

Anomalous course of a coronary artery is a type of congenital coronary artery anomaly. It may represent a benign and incidental finding, but rarely it is a malignant course predisposing patients to life-threatening myocardial ischemia or arrhythmias, depending on where the artery runs.  Clinica...
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Temporal lobe

The temporal lobe is one of the four lobes of the brain (along with the frontal lobe, parietal lobe, and occipital lobe), and largely occupies the middle cranial fossa. Gross anatomy The temporal lobe is the second largest lobe, after the larger frontal lobe, accounting 22% of the total neocor...
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Proximal humeral fracture

Proximal humeral fractures are common upper extremity fractures, particularly in older patients, and can result in significant disability. Epidemiology Proximal humeral fractures represent around 5% of all fractures ?.  They are most common in older populations, especially in osteoporotic ones...
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Sniff test

The fluoroscopic sniff test is a useful addition to diaphragm fluoroscopy and is used to evaluate diaphragmatic contraction and excursion in patients with suspected phrenic nerve palsy or paralysis, breathing difficulties following stroke or recent elevation of a hemidiaphragm on chest radiograp...
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Diaphragmatic paralysis

Diaphragmatic paralysis, diaphragmatic paresis or diaphragmatic palsy may be first suspected when a newly elevated hemidiaphragm is seen on a chest radiograph. Bilateral paralysis is much more serious but often overlooked with an average delay of 2 years to diagnosis. Clinical presentation The...
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Vocal cord paralysis

Vocal cord paralysis/paresis (VCP), also known as vocal fold paralysis/paresis, refers to the impaired mobility of the true vocal cord or fold due to neurologic dysfunction. Clinical presentation Unilateral vocal cord paralysis usually presents with dysphonia (hoarseness), characterized as a b...
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Guillain-Barré syndrome

Guillain-Barré syndrome (GBS) is a heterogeneous group of autoimmune polyradiculopathies, involving sensory, motor, and autonomic nerves. It is the most common cause of rapidly progressive flaccid paralysis. It is believed to be one of a number of related conditions, sharing a similar underlying...
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Morning glory syndrome (eye)

Morning glory disc anomaly (MGDA), also known as morning glory syndrome, is a rare congenital malformation of the optic nerve which is frequently associated with midline abnormalities of the brain and skull 1. Epidemiology Morning glory disc anomaly is rare and is more commonly found in female...
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Area postrema syndrome

Area postrema syndrome is a disorder of the chemoreceptor trigger zone (area postrema) which is located on the medial posteroinferior surface of the medulla oblongata. It is usually a demyelinating disorder, as one of the core clinical characteristics of neuromyelitis optica spectrum disorder 1,...
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Focal hepatic hot spot sign

The focal hepatic hot spot sign, also known as the hot quadrate sign can be seen on technetium 99m sulfur colloid scans of the liver and spleen, as well as CT studies. Radiographic features It occurs as a focal area of increased radiopharmaceutical uptake, or iodinated contrast accumulation, i...

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