Spiculated periosteal reaction represents spicules of new bone-forming along vascular channels and the fibrous bands that anchor periosteum to bone (Sharpey fibres).
Pathology
A spiculated periosteal reaction signifies a rapid underlying process that prevents the formation of new bone under the raised periosteum.
Aetiology
The orientation of the spicules reflects the direction of tumour growth. Spiculated periosteal reactions can be divided into subtypes based on the orientation of the spicules:
1. Wenaden A, Szyszko T, Saifuddin A. Imaging of Periosteal Reactions Associated with Focal Lesions of Bone. Clin Radiol. 2005;60(4):439-56. doi:10.1016/j.crad.2004.08.017 - Pubmed