Squeeze sign

Last revised by Sonam Vadera on 18 Oct 2022

The squeeze sign is a pathognomonic feature of a colonic lipoma, where the lesion is seen to change in size and shape upon compression. This can be demonstrated with a barium enema examination where a well-circumscribed, spherical filling defect will be seen to elongate during peristalsis 1,2. The sign can also be elicited by direct compression during ultrasound scanning. 

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