Question 882
{"accessible":false,"alternatives":[{"id":4435,"text":"T2-weighted cortical region of hyperintensity at the epileptogenic focus"},{"id":4436,"text":"T2-weighted cortical region of hypointensity at the epileptogenic focus"},{"id":4437,"text":"T2-weighted subcortical region of hyperintensity at the epileptogenic focus"},{"id":4438,"text":"T2-weighted subcortical region of hypointensity at the epileptogenic focus"}],"archived":false,"correctAlternativeId":4438,"explanation":"\u003cp\u003e\u003ca href=\"/articles/non-ketotic-hyperglycaemic-seizures\"\u003eNon-ketotic hyperglycaemic seizures\u003c/a\u003e\u0026nbsp;are one of the neurological complications of\u0026nbsp;\u003ca href=\"https://radiopaedia.org/articles/hyperosmolar-hyperglycaemic-state\"\u003enon-ketotic hyperglycaemia\u003c/a\u003e. Clinically, these seizures tend to be partial motor\u0026nbsp;in semiology and are often recurrent (epilepsia partialis continua), with a temporal lobe focus.\u0026nbsp;MRI of the brain is the modality of choice and patients with non-ketotic hyperglycaemic seizures have T2-weighted subcortical regions of hypointensity often with no accompanying anomalies on T1-weighted images or DWI. Imaging findings gradually resolve after glycaemia correction, however evolution of mild atrophy in the region of the epileptogenic focus has been reported.\u0026nbsp;\u003c/p\u003e\u003cp\u003eThis is in stark contrast to classical expected MR findings of seizures (see\u0026nbsp;\u003ca href=\"https://radiopaedia.org/articles/status-epilepticus\"\u003estatus epilepticus\u003c/a\u003e), which include regions of T2-weighted hyperintensity and high diffusion signal on DWI, without any significant long-term sequelae. It is unclear why there are these differences in radiological appearance.\u0026nbsp;\u003c/p\u003e","id":882,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/2381","nextQuestionPath":null,"relatedArticles":[{"id":38710,"title":"Hyperosmolar hyperglycaemic state","link":"/articles/hyperosmolar-hyperglycaemic-state?lang=gb"},{"id":55332,"title":"Non-ketotic hyperglycaemic seizure","link":"/articles/non-ketotic-hyperglycaemic-seizure?lang=gb"}],"alsoUsedIn":[],"stem":"\u003cp\u003eWhat is the typical radiographic\u0026nbsp;MR brain feature\u0026nbsp;seen in a patient with non-ketotic hyperglycaemic seizures?\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/882"}],"attemptsPercentages":[{"alternativeId":"4435","percentage":37},{"alternativeId":"4436","percentage":5},{"alternativeId":"4438","percentage":28},{"alternativeId":"4437","percentage":30}],"promptToLogin":false,"questionManager":false,"articleId":"status-epilepticus"}