Supervised learning (machine learning)

Changed by Frank Gaillard, 12 Oct 2017

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Supervised learning (machine learning)
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Supervised learning is the most common machine learning algorithm used in medical imaging research. It involves training an algorithm from a set of images or data where the output classification is already known 1.

Supervised learning is broken into two subcategories, classification and regression 2. Medical imaging machine learning deals mainly with the classification of images, the most prominent supervised learning classification algorithms are listed below.

Convolution neural network

A convolution neural network is a form of machine learning that exclusively processes array data such as medical images 3.They follow the traditional supervised learning hierarchy whereby analysis and retrospective adjustment of significant sources of training data is its primary purpose 4.

The algorithm is 'multilayered' otherwise known as a 'deep neural network' 5-7

  1. convolution layer
    • the algorithm is provided in input (region of interest)
    • input undergoes feature-based, convolution filters (kernels) creating a feature map
  2. pooling layer
    • feature maps are downsized to a smaller matrix
    • preserves important information by maintaining a maximal pixel value from each filtered set
  3. rectified linear unit
    • during convolution and pooling processes. Some pixels in the matrix may possess negative values
    • the rectified being a unit ensures all negative values as at a zero
  4. fully connected layer
    • each layer will feed into a fully connected layer that presents each separate filtered image as a vote
    • each 'vote' possesses a weight in determining the category of the region of interest

As a region of interest is any known a convolution neural network will undergo backpropagation to adjust the weights of each vote each time a classification is incorrect, otherwise known as the training phase of supervised learning 4

Convolution neural networks will then be subjected to a 'validated training set' to determine if the training phase was successful.

  • -<p><strong>Supervised learning</strong> is the most common machine learning algorithm used in medical imaging research. It involves training an algorithm from a set of images or data where the output classification is already known <sup>1</sup>.</p><p>Supervised learning is broken into two subcategories, classification and regression <sup>2</sup>. Medical imaging machine learning deals mainly with the classification of images, the most prominent supervised learning classification algorithms are listed below. </p><h4>Convolution neural network</h4><p>A convolution neural network is a form of machine learning that exclusively processes array data such as medical images <sup>3</sup>.They follow the traditional supervised learning hierarchy whereby analysis and retrospective adjustment of significant sources of training data is its primary purpose <sup>4</sup>.</p><p>The algorithm is 'multilayered' otherwise known as a 'deep neural network' <sup>5-7</sup></p><ol>
  • -<li>convolution layer<ul>
  • -<li>the algorithm is provided in input (region of interest)</li>
  • -<li>input undergoes feature-based, convolution filters (kernels) creating a feature map</li>
  • -</ul>
  • -</li>
  • -<li>pooling layer<ul>
  • -<li>feature maps are downsized to a smaller matrix</li>
  • -<li>preserves important information by maintaining a maximal pixel value from each filtered set</li>
  • -</ul>
  • -</li>
  • -<li>rectified linear unit<ul>
  • -<li>during convolution and pooling processes. Some pixels in the matrix may possess negative values</li>
  • -<li>the rectified being a unit ensures all negative values as at a zero</li>
  • -</ul>
  • -</li>
  • -<li>fully connected layer<ul>
  • -<li>each layer will feed into a fully connected layer that presents each separate filtered image as a vote</li>
  • -<li>each 'vote' possesses a weight in determining the category of the region of interest</li>
  • -</ul>
  • -</li>
  • -</ol><p>As a region of interest is any known a convolution neural network will undergo backpropagation to adjust the weights of each vote each time a classification is incorrect, otherwise known as the training phase of supervised learning <sup><span style="font-size:10.8333px">4</span></sup>. </p><p>Convolution neural networks will then be subjected to a 'validated training set' to determine if the training phase was successful.</p><p>​</p>
  • +<p><strong>Supervised learning</strong> is the most common machine learning algorithm used in medical imaging research. It involves training an algorithm from a set of images or data where the output classification is already known <sup>1</sup>.</p><p>Supervised learning is broken into two subcategories, classification and regression <sup>2</sup>. Medical imaging machine learning deals mainly with the classification of images.</p><h4> </h4>

References changed:

  • 4. LeCun Y, Bengio Y, Hinton G. Deep learning. Nature. 521 (7553): 436-44. <a href="https://doi.org/10.1038/nature14539">doi:10.1038/nature14539</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/26017442">Pubmed</a> <span class="ref_v4"></span>
  • 5. Chen H, Wang XH, Ma DQ, Ma BR. Neural network-based computer-aided diagnosis in distinguishing malignant from benign solitary pulmonary nodules by computed tomography. Chinese medical journal. 120 (14): 1211-5. <a href="https://www.ncbi.nlm.nih.gov/pubmed/17697569">Pubmed</a> <span class="ref_v4"></span>
  • 7. Lakhani P, Sundaram B. Deep Learning at Chest Radiography: Automated Classification of Pulmonary Tuberculosis by Using Convolutional Neural Networks. Radiology. 284 (2): 574-582. <a href="https://doi.org/10.1148/radiol.2017162326">doi:10.1148/radiol.2017162326</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/28436741">Pubmed</a> <span class="ref_v4"></span>
  • 6. Cicero M, Bilbily A, Colak E, Dowdell T, Gray B, Perampaladas K, Barfett J. Training and Validating a Deep Convolutional Neural Network for Computer-Aided Detection and Classification of Abnormalities on Frontal Chest Radiographs. Investigative radiology. 52 (5): 281-287. <a href="https://doi.org/10.1097/RLI.0000000000000341">doi:10.1097/RLI.0000000000000341</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/27922974">Pubmed</a> <span class="ref_v4"></span>

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