Transfusion-related acute lung injury
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Transfusion related acute lung injury (TRALI) is is defined as non cardiogenic-cardiogenic pulmonary oedema temporally related to transfusion therapy.
It tends to occur within 6 hours after a blood transfusion and requires exclusion of other alternative diagnoses such as sepsis, volume overload.
Radiographic features
Plain filmradiograph
Shows features of pulmonary oedema which can progress to the alveolar and interstitial infiltrates.
Treatment and prognosis
It tends to be self limiting-limiting and treatment is supportive, with a prognosis substantially better than most causes of clinical acute lung injury.
-<p><strong>Transfusion related acute lung injury (TRALI)</strong> is defined as <a href="/articles/non-cardiogenic-pulmonary-oedema" title="non cardiogenic pulmonary oedema ">non cardiogenic pulmonary oedema </a>temporally related to transfusion therapy. </p><p>It tends to occur within 6 hours after a blood transfusion and requires exclusion of other alternative diagnoses such as sepsis, volume overload. </p><h4>Radiographic features</h4><h5>Plain film</h5><p>Shows features of <a href="/articles/pulmonary-oedema" title="pulmonary oedema">pulmonary oedema</a> which can progress to the alveolar and interstitial infiltrates. </p><h4>Treatment and prognosis</h4><p>It tends to be self limiting and treatment is supportive, with a prognosis substantially better than most causes of clinical acute lung injury. </p>- +<p><strong>Transfusion related acute lung injury (TRALI)</strong> is defined as <a href="/articles/non-cardiogenic-pulmonary-oedema">non-cardiogenic pulmonary oedema </a>temporally related to transfusion therapy. </p><p>It tends to occur within 6 hours after a blood transfusion and requires exclusion of other alternative diagnoses such as sepsis, volume overload. </p><h4>Radiographic features</h4><h5>Plain radiograph</h5><p>Shows features of <a href="/articles/pulmonary-oedema">pulmonary oedema</a> which can progress to the alveolar and interstitial infiltrates. </p><h4>Treatment and prognosis</h4><p>It tends to be self-limiting and treatment is supportive, with a prognosis substantially better than most causes of clinical acute lung injury. </p>
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