Tumor spread through air spaces

Changed by Bruno Di Muzio, 1 Jul 2019

Updates to Article Attributes

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Tumour spread through air spaces (STAS) is a relatively recently recognised pattern of invasion in lung adenocarcinoma. According to the 2015 WHO classification, STAS is defined as “micropapillary clusters, solid nests, or single cells spreading within air spaces beyond the edge of the main tumour” 2-3. Presence of STAS is considered a significant risk factor of recurrence in small lung adenocarcinomas treated with limited resection. 

See also

  • -<p><strong>Tumour spread through air spaces (STAS) </strong>is a relatively recently recognised pattern of invasion in <a href="/articles/lung-adenocarcinoma">lung adenocarcinoma</a>. According to the 2015 WHO classification, STAS is defined as “micropapillary clusters, solid nests, or single cells spreading within air spaces beyond the edge of the main tumour” <sup>2-3</sup>. Presence of STAS is considered a significant risk factor of recurrence in small lung adenocarcinomas treated with limited resection. </p><h4>See also</h4><ul><li>
  • -<a href="/articles/lung-cancer-invasion-patterns">lung cancer invasion patterns</a><ul>
  • -<li><strong>tumour spread through air spaces (STAS)</strong></li>
  • -<li><a href="/articles/presence-of-non-lepidic-patterns-such-as-acinar-papillary-solid-or-micropapillary">presence of non-lepidic patterns such as acinar, papillary, solid, or micropapillary</a></li>
  • -<li><a href="/articles/myofibroblastic-stroma-associated-with-invasive-tumour-cells">myofibroblastic stroma associated with invasive tumour cells</a></li>
  • -<li><a href="/articles/vascular-invasion-in-lung-cancer">vascular invasion</a></li>
  • -<li><a href="/articles/visceral-pleural-invasion">pleural invasion</a></li>
  • -</ul>
  • -</li></ul>
  • +<p><strong>Tumour spread through air spaces (STAS) </strong>is a relatively recently recognised pattern of invasion in <a href="/articles/lung-adenocarcinoma">lung adenocarcinoma</a>. According to the 2015 WHO classification, STAS is defined as “micropapillary clusters, solid nests, or single cells spreading within air spaces beyond the edge of the main tumour” <sup>2-3</sup>. Presence of STAS is considered a significant risk factor of recurrence in small lung adenocarcinomas treated with limited resection. </p>

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