Wheel within a wheel sign (hepatic candidiasis)
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This sign is seen in USGdescribes one of several possible ultrasound findings of hepatic candidiasis and described as . The finding consists of a round lesion with three layers corresponding to the following histopathologic changes 2:
- peripheral hypoechoic area (fibrosis)
- middle hyperechoic area (inflammatory cells)
- central hypoechoic area (necrosis containing
fungi) surrounded by
The histopathologic correlates were shown via an echogenic zone (inflammatory cells)animal model.
This appearance is in contrast to the more common bull’s-eye sign for reverse echogeniticityultrasound finding, as itwhich is consists of a central echogenic nidus surrounded by a hypoechoic rim.
-<p>This sign is seen in USG of patient with the <a href="/cases/hepatic-candidiasis" title="hepatic candidiasis">hepatic candidiasis</a> and described as central hypoechoic area (necrosis containing fungi) surrounded by an echogenic zone (inflammatory cells).</p><p>Differs from <a href="/articles/bulls-eye-sign-general" title="bull’s-eye sign">bull’s-eye sign</a> for reverse echogeniticity, as it consists a central echogenic nidus surrounded by a hypoechoic rim.</p>- +<p>This sign describes one of several possible ultrasound findings of <a href="/cases/hepatic-candidiasis">hepatic candidiasis</a>. The finding consists of a round lesion with three layers corresponding to the following histopathologic changes <sup>2</sup>:</p><ul>
- +<li>peripheral hypoechoic area (fibrosis)</li>
- +<li>middle hyperechoic area (inflammatory cells)</li>
- +<li>central hypoechoic area (necrosis containing</li>
- +</ul><p>The histopathologic correlates were shown via an animal model.</p><p>This appearance is in contrast to the more common <a href="/articles/target-sign-disambiguation">bull’s-eye sign</a> ultrasound finding, which is consists of a central echogenic nidus surrounded by a hypoechoic rim.</p>
References changed:
- 1. Lawrence PH, Holt SC, Levi CS, Gough JC. Ultrasound case of the day. Hepatosplenic candidiasis. (1994) Radiographics : a review publication of the Radiological Society of North America, Inc. 14 (5): 1147-9. <a href="https://doi.org/10.1148/radiographics.14.5.7991822">doi:10.1148/radiographics.14.5.7991822</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/7991822">Pubmed</a> <span class="ref_v4"></span>
- 1. Lawrence PH, Holt SC, Levi CS, Gough JC. Ultrasound case of the day. Hepatosplenic candidiasis. (1994) Radiographics : a review publication of the Radiological Society of North America, Inc. 14 (5): 1147-9. <a href="https://doi.org/10.1148/radiographics.14.5.7991822">doi:10.1148/radiographics.14.5.7991822</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/7991822">Pubmed</a> <span class="ref_v4"></span>
- 2. Pastakia B, Shawker TH, Thaler M, O'leary T, Pizzo PA. Hepatosplenic candidiasis: wheels within wheels. (1988) Radiology. 166 (2): 417-21. <a href="https://doi.org/10.1148/radiology.166.2.3275982">doi:10.1148/radiology.166.2.3275982</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/3275982">Pubmed</a> <span class="ref_v4"></span>
- http://radiology.rsna.org/content/166/2/417.abstract?keytype2=tf_ipsecsha&ijkey=ed5715efd538c546c4b409988ebb8908de7db99c
- 1. Lawrence PH, Holt SC, Levi CS, Gough JC. Ultrasound case of the day. Hepatosplenic candidiasis. (1994) Radiographics : a review publication of the Radiological Society of North America, Inc. 14 (5): 1147-9. <a href="https://doi.org/10.1148/radiographics.14.5.7991822">doi:10.1148/radiographics.14.5.7991822</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/7991822"></a> <span class="ref_v4"></span>
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