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Cerebral metastasis

Case contributed by Dr Muhammad Asadullah Munir


This is a treated case of carcinoma of the breast, presented with right-sided weakness and slurring of speech.

Patient Data

Age: 70 years
Gender: Female

There is a fairly well circumscribed lobulated hyperdense intra-axial space occupying lesion in left area centrum semiovale extending towards corona radiata creeping along the body of left lateral ventricle reaching upto the left basal ganglia and thalamus with suggestion of possible subependymal infiltration in body of the left lateral ventricle. This is measuring approximately 4.0 x 2.3 cm in AP and TR dimensions. There is associated significant disproportionate vasogenic edema in left cerebral hemisphere including basal ganglia and thalamus, causing mass effect resulting in effacement of the left lateral ventricle and mild contralateral midline shift of 0.3 cm. Another focal area of vasogenic edema is present in right corona radiata.

In keeping with history of treated carcinoma of the breast, imaging features are highly suggestive of brain metastasis. Other differential would include cerebral abscess. Contrast enhanced MRI is recommended for further evaluation.

Case Discussion

This patient had a history of treated breast carcinoma. The imaging features suggest metastasis (secondary to primary breast carcinoma). Other differentials would include cerebral abscess (in the setting of an immunocompromised state due to chemotherapy). MRI brain with contrast should be done as it is more sensitive in detecting subtle metastatic deposits. 

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Case information

rID: 80088
Published: 21st Jul 2020
Last edited: 21st Jul 2020
Inclusion in quiz mode: Included
Institution: Dr Ziauddin Hospital

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