Cytotoxic lesions of the corpus callosum (CLOCCs)
Diagnosis almost certain
Disclosures
- updated 26 Jan 2024:
Nothing to disclose
Updates to Study Attributes
Findings
was changed:
There is a small area of signal alteration in the splenium of the corpus callosum which appears hypointense on T1W images, hyperintense on T2W/FLAIR images with true diffusion restriction on DWI, and no significant enhancement on T1W post-contrast images.
Images Changes:
Image 12 MRI (T1) ( update )
![](https://prod-images-static.radiopaedia.org/images/64206407/37cd596196efeb9f835ab49f013c977dcc238c6ba51576434a534536373bdd19_thumb.jpeg)
Annotation 8533
changed from 1 arrow,1 label to 1 arrow,1 label.
Image 12 MRI (T2) ( update )
![](https://prod-images-static.radiopaedia.org/images/64206382/e1a2406357eec9d719dab075318f1b3183d7dd6b970af2616cea9fbc7fef9b9d_thumb.jpeg)
Annotation 8534
changed from 1 label to 1 label.
Image 12 MRI (DWI) ( update )
![](https://prod-images-static.radiopaedia.org/images/64206507/86e13e61729886f858a2730b72f150ab228e8d2e1ce4e2535b982b40a0f29e5d_thumb.jpeg)
Annotation 8535
changed from 1 arrow to 1 arrow.
Image 25 MRI (T1 C+ fat sat) ( update )
![](https://prod-images-static.radiopaedia.org/images/64206680/c0945c2ba46250f6ace9c012dabf6faf3ed446e2baa5e55495c2e5572dd610ef_thumb.jpeg)
Annotation 8536
changed from 1 label to 1 label.
Updates to Case Attributes
Body
was changed:
Imaging findings are suggestive of cytotoxic lesions of the corpus callosum (CLOCCs), secondary to the hyponatraemia.
Co-author: Dr Vivek Ranjan (Paediatrician).
-<p>Imaging findings are suggestive of cytotoxic lesions of the corpus callosum (CLOCCs), secondary to the hyponatraemia.</p><p>Co-author: Dr Vivek Ranjan (Paediatrician).</p>- +<p>Imaging findings are suggestive of <a href="/articles/cytotoxic-lesions-of-the-corpus-callosum-cloccs" title="Cytotoxic lesions of the corpus callosum (CLOCCs)">cytotoxic lesions of the corpus callosum (CLOCCs)</a>, secondary to hyponatraemia.</p><p>Co-author: Dr Vivek Ranjan (Paediatrician).</p>
Systems changed:
- Paediatrics