Cytotoxic lesions of the corpus callosum (CLOCCs)

Case contributed by Keshaw Kumar , 22 Dec 2023
Diagnosis almost certain
Changed by Ryan Thibodeau, 25 Mar 2024
Disclosures - updated 26 Jan 2024: Nothing to disclose

Updates to Study Attributes

Findings was changed:

There is a small area of signal alteration in the splenium of the corpus callosum which appears hypointense on T1W images, hyperintense on T2W/FLAIR images with true diffusion restriction on DWI, and no significant enhancement on T1W post-contrast images.

Images Changes:

Image 12 MRI (T1) ( update )

Annotation 8533 changed from 1 arrow,1 label to 1 arrow,1 label.

Image 12 MRI (T2) ( update )

Annotation 8534 changed from 1 label to 1 label.

Image 12 MRI (DWI) ( update )

Annotation 8535 changed from 1 arrow to 1 arrow.

Image 25 MRI (T1 C+ fat sat) ( update )

Annotation 8536 changed from 1 label to 1 label.

Updates to Case Attributes

Body was changed:

Imaging findings are suggestive of cytotoxic lesions of the corpus callosum (CLOCCs), secondary to the hyponatraemia.

Co-author: Dr Vivek Ranjan (Paediatrician).

  • -<p>Imaging findings are suggestive of cytotoxic lesions of the corpus callosum (CLOCCs), secondary to the hyponatraemia.</p><p>Co-author: Dr Vivek Ranjan (Paediatrician).</p>
  • +<p>Imaging findings are suggestive of <a href="/articles/cytotoxic-lesions-of-the-corpus-callosum-cloccs" title="Cytotoxic lesions of the corpus callosum (CLOCCs)">cytotoxic lesions of the corpus callosum (CLOCCs)</a>, secondary to hyponatraemia.</p><p>Co-author: Dr Vivek Ranjan (Paediatrician).</p>

Systems changed:

  • Paediatrics

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.