Endolymphatic sac tumor
Updates to Case Attributes
The patient went on to have a resection.
Histology
MACROSCOPIC DESCRIPTION:
An irregularly shaped piece of tan tissue, 14x9x6mm.
MICROSCOPIC DESCRIPTION:
The sections show a moderately cellular tumour. It forms elongated nests and acinar-like structures. Some contain calcific deposits and psammoma bodies. The tumour cells have round nuclei, inconspicuous nucleoli and moderate amounts of 'oncocytic type' eosinophilic cytoplasm. T
heThe tumour cells are CAM5.2, AE1/3, CK7, EMA, S-100 and SOX-10 positive. Progesterone receptor, melan-A, synaptophysin, TTF-1 and thyroglobulin are negative.
The PAS stain shows no fungi. The Ziehl-Neelsen stain shows no acid fast bacilli.
Though the architecture is not quite papillary but given the immunoprofile and the site, the features are consistent with papillary tumour of the endolymphatic sac.
DIAGNOSIS:
-<p>The patient went on to have a resection. </p><p><strong>Histology</strong></p><p>MACROSCOPIC DESCRIPTION:</p><p>An irregularly shaped piece of tan tissue, 14x9x6mm. </p><p>MICROSCOPIC DESCRIPTION:</p><p>The sections show a moderately cellular tumour. It forms elongated nests and acinar-like structures. Some contain calcific deposits and psammoma bodies. The tumour cells have round nuclei, inconspicuous nucleoli and moderate amounts of 'oncocytic type' eosinophilic cytoplasm. T</p><p>he tumour cells are CAM5.2, AE1/3, CK7, EMA, S-100 and SOX-10 positive. Progesterone receptor, melan-A, synaptophysin, TTF-1 and thyroglobulin are negative.</p><p>The PAS stain shows no fungi. The Ziehl-Neelsen stain shows no acid fast bacilli.</p><p>Though the architecture is not quite papillary but given the immunoprofile and the site, the features are consistent with papillary tumour of the endolymphatic sac.</p><p>DIAGNOSIS:</p><p><a title="Endolymphatic sac tumour" href="/articles/endolymphatic-sac-tumour">Papillary tumour of the endolymphatic sac.</a></p>- +<p>The patient went on to have a resection. </p><p><strong>Histology</strong></p><p>MACROSCOPIC DESCRIPTION:</p><p>An irregularly shaped piece of tan tissue, 14x9x6mm. </p><p>MICROSCOPIC DESCRIPTION:</p><p>The sections show a moderately cellular tumour. It forms elongated nests and acinar-like structures. Some contain calcific deposits and psammoma bodies. The tumour cells have round nuclei, inconspicuous nucleoli and moderate amounts of 'oncocytic type' eosinophilic cytoplasm.</p><p>The tumour cells are CAM5.2, AE1/3, CK7, EMA, S-100 and SOX-10 positive. Progesterone receptor, melan-A, synaptophysin, TTF-1 and thyroglobulin are negative.</p><p>The PAS stain shows no fungi. The Ziehl-Neelsen stain shows no acid fast bacilli.</p><p>Though the architecture is not quite papillary but given the immunoprofile and the site, the features are consistent with papillary tumour of the endolymphatic sac.</p><p>DIAGNOSIS:</p><p><a href="/articles/endolymphatic-sac-tumour">Papillary tumour of the endolymphatic sac.</a></p>
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