Fundic gland polyp (histology)
Diagnosis certain
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The production of HCl requires enormous amounts of energy so acid-producing parietal cells are jam packed with energy producing mitochondria; these stain strongly with acidic dyes including eosin (the 'E' in H&E).
The main function of chief cells is the production of the (pre-)protein pepsinogen so chief cells are packed with ribosome lined (rough) endoplasmic reticulum; ribosomes stain with basic dyes including haematoxylin (the 'H' in H&E)
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