Granulomatosis with polyangitis - pulmonary cavities

Case contributed by Bruno Di Muzio , 1 Jan 2014
Diagnosis almost certain
Changed by Bruno Di Muzio, 1 Jan 2014

Updates to Case Attributes

Diagnostic Certainty was set to .
Presentation was changed:
Cough and fever. Recurrence of symptoms three months after her last hospitalizationhospitalisation.
Age changed from 34 to 34-year-old.
Body was changed:

Granulomatosis with polyangitis (Wegener granulomatosis), is a multi-system systemic necrotizing non-caeseating-caseating granulomatous vasculitis affecting small to medium sized-sized arteries, capillaries and veins, and the lungs are the most frequently involved organ, seen in 95% of cases.

The most common radiological presentation is with multiple nodules randomly distributed. In approximately half of cases, some of the nodules demonstrate cavitation, which is best seen with CT.

This case showshows multiple cavities and the patient hasrecurrent pulmonary infections (caused by usual bacteria). On the last hospitalization she was submitted to thoracic drainage and subsequent surgical intervention.

Patient was confirmed to haveGranulomatosis with polyangitispolyangiitis(Wegener granulomatosis).

  • -<p><a title="Granulomatosis with polyangitis (GPA)" href="/articles/granulomatosis-with-polyangitis">Granulomatosis with polyangitis</a> (Wegener granulomatosis), is a multi-system systemic necrotizing non-caeseating granulomatous <a title="Vasculitis" href="/articles/vasculitis">vasculitis</a> affecting small to medium sized arteries, capillaries and veins, and the lungs are the most frequently involved organ, seen in 95% of cases.</p><p><span style="color:rgb(64, 64, 64); font-family:open sans,sans-serif; line-height:17.27272605895996px">The most common radiological presentation is with multiple nodules randomly distributed</span><span style="color:rgb(64, 64, 64); font-family:open sans,sans-serif; line-height:17.27272605895996px">. In approximately half of cases, some of the nodules demonstrate cavitation, which is best seen with CT.</span></p><p><span style="color:rgb(64, 64, 64); font-family:open sans,sans-serif; line-height:17.27272605895996px">This case show multiple cavities and the patient has </span><font color="#404040" face="Open Sans, sans-serif"><span style="line-height:17.27272605895996px">recurrent pulmonary infections (caused by usual bacteria). On the last hospitalization she was submitted to thoracic drainage and subsequent surgical intervention.</span></font></p><p><span style="color:rgb(0, 0, 0); font-family:helvetica,arial,sans-serif; font-size:11.818181991577148px; line-height:16.363636016845703px">Patient was confirmed to have </span><a title="Granulomatosis with polyangitis (GPA)" style="font-size: 13px; line-height: 1.6em;" href="/articles/granulomatosis-with-polyangitis">Granulomatosis with polyangitis</a><span style="font-size:13px; line-height:1.6em"> </span><span style="font-size:13px; line-height:1.6em">(Wegener granulomatosis).</span></p>
  • +<p><a href="/articles/granulomatosis-with-polyangiitis">Granulomatosis with polyangitis</a> (Wegener granulomatosis), is a multi-system systemic necrotizing non-caseating granulomatous <a href="/articles/vasculitis">vasculitis</a> affecting small to medium-sized arteries, capillaries and veins, and the lungs are the most frequently involved organ, seen in 95% of cases.</p><p>The most common radiological presentation is with multiple nodules randomly distributed. In approximately half of cases, some of the nodules demonstrate cavitation, which is best seen with CT.</p><p>This case shows multiple cavities and the patient has recurrent pulmonary infections (caused by usual bacteria). On the last hospitalization she was submitted to thoracic drainage and subsequent surgical intervention.</p><p>Patient was confirmed to have <a href="/articles/granulomatosis-with-polyangiitis">Granulomatosis with polyangiitis</a> (Wegener granulomatosis).</p>

Updates to Study Attributes

Caption was added:
Chest X-ray

Updates to Study Attributes

Caption was added:
CT Chest

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