Radiopaedia's 25% off Courses and All-Access Passes ends tomorrow! EXPLORE OUR COURSES

Hypoxic-ischemic encephalopathy

Case contributed by Dr Ayaz Hidayatov


A 50-year-old comatose man presented an episode of apnea during surgery with subsequent cardiac arrest and cardiopulmonary resuscitation.

Patient Data

Age: 50 years
Gender: Male

Non-contrast CT performed 5-6 hours after surgery and was interpreted as normal.


MR obtained after 24 hours after the hypoxic-ischemic episode and T2WI and FLAIR demonstrate mild gyral swelling with pronounced grey-white matter differentiation of the bilateral cerebral and cerebellar hemispheres. There is also increased signal in bilateral basal ganglia on FLAIR and T2WI.

DW images show mild cortical hyperintensity of the grey-white matter interface. ADC shows severe cortical restricted diffusion.

Findings are suggestive of hypoxic-ischemic encephalopathy.

Case Discussion

Hypoxic-ischemic encephalopathy results from a global rather than ischemic insult, either due to ischemia from hypoperfusion or hypoxia. In most cases, this is due to a cardiac or respiratory arrest.

PlayAdd to Share

Case information

rID: 57525
Published: 30th Dec 2017
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.