Invasive ductal breast carcinoma

Case contributed by Ibdaa Khatatbeh
Diagnosis certain

Presentation

The patient presented to the surgery clinic complaining of a right breast lump. Negative family history of breast cancer.

Patient Data

Age: 50 years
Gender: Female

Contact, 3D and compression

mammography

Breast composition: Heterogeneously dense breast, which may obscure small masses, ACR C.

There is architectural distortion seen in the right mid-outer region, associated with clustered pleomorphic calcifications and mild areolar skin thickening.

Bilateral inverted nipples.

No left sided dominant spiculated lesion.

No left sided suspicious clustered microcalcification.

ultrasound

The right breast shows a spiculated hypoechoic lesion with a hyperechoic halo, seen at 9:00 measuring about 4.5 x 3.5 x 2.7 cm, the lesion appears to involve the nipple.

There is a right axillary lymph node with a thickened cortex however it appears oval with a preserved fatty hilum.

The left breast shows normal fibroglandular tissue without evidence of cystic or solid focal lesion apart from a small cyst in the upper outer quadrant.

Benign-looking lymph nodes in left axillae.

Case Discussion

This is a BI-RADS V lesion, highly suggestive of malignancy regarding the right breast. A biopsy was performed.

Histopathology

GROSS: Specimen fixed labeled with patient's name consists of 2 grey-white soft tissue needle core biopsies, the largest 2 x 0.2 cm. Submitted all in one cassette.

MICROSCOPIC: Sections reveal breast core biopsies infiltrated by invasive ductal carcinoma of intermediate nuclear grade with wide areas of necrosis.

DIAGNOSIS: right breast mass, trucut biopsy. Consistent with invasive ductal carcinoma, NOS.

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