Nasopharyngeal carcinoma with skull base invasion

Case contributed by Ian Bickle , 17 May 2017
Diagnosis certain
Changed by Tim Luijkx, 1 Jun 2017

Updates to Case Attributes

Presentation was changed:
TeenagersTeenager with leftlevel V mass.One week history given. On fibroscopy adenoidal tissue and left nasal polyp.Bled on touch.
Age changed from 15 to 15 years.
Body was changed:

This teenage patient presented with advanced nasopharyngeal metastatic disease. 

The case demonstrates the combined value to MRI and CT in head and neck malignancies, especially those involving the skull base.

The anatomical spaces of the head and neck are well demonstrated on this case in particular the sphenopalantinesphenopalatine foramen and pterygopalantinepterygopalatine fossa, as the tumour extends into the expands these spaces.

Ultrasound guided biopsy of the neck node was undertaken.

HISTOLOGY: Metastatic undifferentiated carcinoma

  • -<p>This teenage patient presented with advanced nasopharyngeal metastatic disease. </p><p>The case demonstrates the combined value to MRI and CT in head and neck malignancies, especially those involving the skull base.</p><p>The anatomical spaces of the head and neck are well demonstrated on this case in particular the sphenopalantine foramen and pterygopalantine fossa, as the tumour extends into the expands these spaces.</p><p>Ultrasound guided biopsy of the neck node was undertaken.</p><p>HISTOLOGY: Metastatic undifferentiated carcinoma</p>
  • +<p>This teenage patient presented with advanced nasopharyngeal metastatic disease. </p><p>The case demonstrates the combined value to MRI and CT in head and neck malignancies, especially those involving the skull base.</p><p>The anatomical spaces of the head and neck are well demonstrated on this case in particular the sphenopalatine foramen and pterygopalatine fossa, as the tumour extends into the expands these spaces.</p><p>Ultrasound guided biopsy of the neck node was undertaken.</p><p>HISTOLOGY: Metastatic undifferentiated carcinoma</p>

Updates to Study Attributes

Findings was changed:

Large well defined enhancing mass centred on the left Fossafossa of Rosenmuller with bulk dimensions of 5.4 x 4.4cm.  The mass extends inferiorly on the left to the oropharynx and superiorly into and almost completely filling the sphenoid sinus.  On the left the tumour involves the posterior nasal canal.

The mass crosses right of the midline at the level of the nasopharynx and on the left abuts 180 degrees of the internal carotid artery.

A 8mm8 mm tongue of tissue extends into and widens the left sphenopalantinesphenopalatine foramen and pterygopalantinepterygopalatine fossa into the pterygomaxillary fissuetissue.

Pituitary fossa and floor of the anterior cranial fossa are intact.  The left medial pterygoid plate and posterior aspect of the bone nasal septum is irregular with cortical disruption.

Obstructive fluid in the left maxillary sinus.  Obstructive fluid in the left mastoid due to EusthacianEustachian tube obstruction from the mass.

Malignant 4.9cm.9 cm left level V nodes with some smaller adjacent sub-centrimetre-centimetre nodes.

Left level III nodes upto 15mmup to 15 mm.    Left 1B upto 13mmup to 13 mm.

Updates to Study Attributes

Findings was changed:

Large well defined enhancing mass centred on the left Fossafossa of Rosenmuller with bulk dimensions of 5.4 x 4.4cm.4 cm.  The mass extends inferiorly to the oropharynx and superiorly into and almost completely filling the sphenoid sinus.  On the left the tumour involves the posterior nasal canal.

The mass crosses right of the midline at the level of the nasopharynx and on the left abuts 180 degrees of the internal carotid artery.

A 8mm tongue of tissue extends into and widens the left sphenopalantinesphenopalatine foramen and pterygopalantinepterygopalatine fossa into the pterygomaxillary fissuetissue.

Pituitary fossa and floor of the anterior cranial fossa are intact.  The left medial pterygoid plate and posterior aspect of the bone nasal septum is irregular with cortical disruption.

Obstructive fluid in the left maxillary sinus.  Obstructive fluid in the left mastoid due to EusthacianEustachian tube obstruction from the mass.

Malignant 4.9cm.9 cm left level V nodes with some smaller adjacent sub-centrimetre-centimetre nodes.

Left level III nodes upto 15mmup to 15 mm.    Left 1B upto 13mmup to 13 mm.

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