Physiological uptake of Ga-68 DOTATATE at the uncinate process of pancreas
Updates to Case Attributes
This case illustrates part of the imaging work up for a neuroendocrine tumour. CT Chestchest, Abdomenabdomen, and pelvis and GaTate (gallium-68 DOTA-TATE) PET/CT were normal with no underlying carcinoid tumour.
The increased uptake seen in the pancreatic head is a recognised physiological finding that happens in some of the scans and should be interpreted with caution. SUV quantification is advised to avoid false positives, as the physiological uptake is similar to the uptake in the liver (uptake ratio head to liver SUVav < 1.4) 1.
The 5-HIAA was only mildly elevated in this patient and, in the context of a normal of GaTate PET/CT, carcinoid syndrome was considered unlikely to explain the patient's symptoms (flushing and diarrhoea).
-<p>This case illustrates part of the imaging work up for a neuroendocrine tumour. CT Chest, Abdomen, and pelvis and GaTate PET/CT were normal with no underlying carcinoid tumour. </p><p>The increased uptake seen in the pancreatic head is a recognised physiological finding that happens in some of the scans and should be interpreted with caution. SUV quantification is advised to avoid false positives, as the physiological uptake is similar to the uptake in the liver (uptake ratio head to liver SUVav < 1.4) <sup>1</sup>.</p><p>The 5-HIAA was only mildly elevated in this patient and, in the context of a normal of GaTate PET/CT, carcinoid syndrome was considered unlikely to explain the patient's symptoms (flushing and diarrhoea). </p>- +<p>This case illustrates part of the imaging work up for a neuroendocrine tumour. CT chest, abdomen, and pelvis and GaTate (gallium-68 DOTA-TATE) PET/CT were normal with no underlying carcinoid tumour. </p><p>The increased uptake seen in the pancreatic head is a recognised physiological finding that happens in some of the scans and should be interpreted with caution. SUV quantification is advised to avoid false positives, as the physiological uptake is similar to the uptake in the liver (uptake ratio head to liver SUVav < 1.4) <sup>1</sup>.</p><p>The 5-HIAA was only mildly elevated in this patient and, in the context of a normal of GaTate PET/CT, carcinoid syndrome was considered unlikely to explain the patient's symptoms (flushing and diarrhoea). </p>
Updates to Study Attributes
No focal abnormal uptake is seen in the small bowel or pancreas. No abnormal uptake is seen in the lung fields. No nodal or distant metastases.
Further findings: Physiologicphysiologic uptake is seen in the uncinate process of the pancreas. There is a symmetric uptake in the partially calcified mediastinal and hilar lymph nodes representing reactive aetiology. The distribution of radiotracer elsewhere is physiologic.