Reactive lymph node hyperplasia

Case contributed by Dennis Odhiambo Agolah
Diagnosis certain


Patient with testicular pain on and off with a left inguinal node.

Patient Data

Age: 30 years
Gender: Male

A large (4.7 x 2.04 cm in size; cortical thickness = 0.81 cm), solitary left inguinal lymph node that maintain its cortical-medullary differentiation (outer cortex, para-cortex and its medulla zones) however, with chaotic vasculature within its parenchyma is noted.


The smears are densely cellular consisting of numerous variably sized lymphocytes at various stages of maturation. There are no granulomas nor atypical cells seen.

Diagnosis: Left inguinal node- Reactive lymph node hyperplasia.

Case Discussion

Solitary moderately enlarged left inguinal lymph node with chaotic parenchymal arterial and venous vasculature. Fine needle aspiration cytology (FNAC) of the node proved it to be a reactive lymph node hyperplasia. The scrotal contents (not shown) were unremarkable.

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