Solitary fibrous tumor (hemangiopericytoma) metastases

Case contributed by Lukas Valkovic , 26 Sep 2018
Diagnosis almost certain
Changed by Frank Gaillard, 28 Nov 2021

Updates to Case Attributes

Title was changed:
Meningeal haemangiopericytomaSolitary fibrous tumour (haemangiopericytoma) metastases
Age changed from 40 to 40 years.
Body was changed:

Patient with sensations in the right ear during pregnancy, which worsened after childbirth (tingling of the face). Initial CT and MRI with the finding of a large tumortumour in the right temporal lobe with an infiltration of the petrosal part of the temporal bone. Subsequently treated with preoperative embolization thenthan with a partial surgical resection followed by radiotherapy 5 years ago.

The recent follow-up study shows multiple lesions in both breasts, muscles of the abdominal/thoracic wall, liver, lungs and probably kidney which show similar characteristics. They are not easily recognizable in native CT/MRI and show no increase in glucose metabolism on PET. Their vivid early enhancement, distribution and patients history points to hemangiopericytoma metastases. 

Note: Due to molecular/genetic similarities haemangiopericytomas are no longer recognised as distinct entities. Instead, they represent cellular higher-grade solitary fibrous tumours. In the 2016 revised 4th Edition of the WHO classification of CNS tumours, they were grouped together under one diagnosis (solitary fibrous tumour/haemangiopericytoma), and in the 2021 5th edition the term haemangiopericytoma was dropped entirely. 

  • -<p>Patient with sensations in the right ear during pregnancy, which worsened after childbirth (tingling of the face). Initial CT and MRI with the finding of a large tumor in the right temporal lobe with an infiltration of petrosal part of the temporal bone. Subsequently treated with preoperative embolization then with a partial surgical resection followed by radiotherapy 5 years ago.</p><p>The recent follow-up study shows multiple lesions in both breasts, muscles of the abdominal/thoracic wall, liver, lungs and probably kidney which show similar characteristics. They are not easily recognizable in native CT/MRI and show no increase in glucose metabolism on PET. Their vivid early enhancement, distribution and patients history points to hemangiopericytoma metastases. </p>
  • +<p>Patient with sensations in the right ear during pregnancy, which worsened after childbirth (tingling of the face). Initial CT and MRI with the finding of a large tumour in the right temporal lobe with infiltration of the petrosal part of the temporal bone. Subsequently treated with preoperative embolization than with a partial surgical resection followed by radiotherapy 5 years ago.</p><p>The recent follow-up study shows multiple lesions in both breasts, muscles of the abdominal/thoracic wall, liver, lungs and probably kidney which show similar characteristics. They are not easily recognizable in native CT/MRI and show no increase in glucose metabolism on PET. Their vivid early enhancement, distribution and patients history points to hemangiopericytoma metastases. </p><p> </p><p><strong>Note:</strong> Due to molecular/genetic similarities haemangiopericytomas are no longer recognised as distinct entities. Instead, they represent cellular higher-grade solitary fibrous tumours. In the 2016 revised 4th Edition of the <a href="/articles/who-classification-of-cns-tumours-1">WHO classification of CNS tumours</a>, they were grouped together under one diagnosis (solitary fibrous tumour/haemangiopericytoma), and in the 2021 5th edition the term haemangiopericytoma was dropped entirely. </p>

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Meningeal haemangiopericytoma metastases
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