Solitary plasmacytoma

Case contributed by Prashant Gupta , 16 May 2012
Diagnosis almost certain
Changed by Mostafa Elfeky, 4 Feb 2023
Disclosures - updated 11 May 2022: Nothing to disclose

Updates to Case Attributes

Age changed from 50 to 50 years.
Body was changed:

Although many vertebral lesions show low signal on t1 with high signal on t2 the "mini brain" sign is considered to be fairly characterestic of a solitary plasmacytoma.

Some authors consider it typical enough to forego a biopsy and start treatment1.

  • -<p>Although many vertebral lesions show low signal on t1 with high signal on t2 the "<a href="/articles/mini-brain" title="mini brain">mini brain</a>" sign is considered to be fairly characterestic of a <a href="/articles/solitary-bone-plasmacytoma-1" title="Solitary bone plasmacytoma (SBP)">solitary plasmacytoma</a>.</p><p>Some authors consider it typical enough to forego a biopsy and start treatment.</p>
  • +<p>Although many vertebral lesions show low signal on t1 with high signal on t2 the "<a href="/articles/solitary-bone-plasmacytoma-1" title="Mini brain sign">mini brain</a>" sign is considered to be fairly characterestic of a <a href="/articles/solitary-bone-plasmacytoma-1" title="Solitary bone plasmacytoma (SBP)">solitary plasmacytoma</a>. Some authors consider it typical enough to forego a biopsy and start treatment <sup>1</sup>.</p>

References changed:

  • 1. Major NM, Helms CA, Richardson WJ. The "mini brain": plasmacytoma in a vertebral body on MR imaging. AJR Am J Roentgenol. 2000;175 (1): 261-3. AJR Am J Roentgenol.
  • Major NM, Helms CA, Richardson WJ. The "mini brain": plasmacytoma in a vertebral body on MR imaging. AJR Am J Roentgenol. 2000;175 (1): 261-3. AJR Am J Roentgenol (citation) - Pubmed citation

Systems changed:

  • Spine

Updates to Study Attributes

Caption was changed:
CT spineL1 vertebra
Findings was changed:

A correlation CT was performed. There is an expansile soft tissue lesion involving only the L1 vertebra. Prominent residual thickened trabeculae are seen giving a "MINI BRAIN"mini brain" appearance.

Images Changes:

Image CT (bone window) ( update )

Perspective was set to Axial.
Specifics changed from non-contrast to bone window.

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