Thalidomide embryopathy
Diagnosis certain
Disclosures
- updated 20 Jan 2023:
Nothing to disclose
Updates to Case Attributes
Presentation
was changed:
Rotational force, reduced ROMrange of motion, increasing pain, fracture. Known thalidomide exposure.
Body
was changed:
Obvious skeletal malformation of the upper distal limb in a patient with a known history of thalidomide.
The illness known as thalidomide embryopathy, which is caused by in utero-utero exposure to the drug, is distinguished by a number of foetal malformations. The majority of thalidomide exposure in foetuses happened between 1957 and 1961, when it was prescribed to pregnant women to relieve morning sickness.
It can lead to limb, facial and cardiac abnormalities or limited growth.
-<p>Obvious skeletal malformation of the upper distal limb in a patient with a known history of <a href="/articles/thalidomide-embryopathy" title="Thalidomide embryopathy">thalidomide</a>.</p><p>The illness known as thalidomide embryopathy, which is caused by <em>in utero</em> exposure to the drug, is distinguished by a number of foetal malformations. The majority of thalidomide exposure in foetuses happened between 1957 and 1961, when it was prescribed to pregnant women to relieve morning sickness.</p><p>It can lead to limb, facial and cardiac abnormalities or limited growth.</p>- +<p>Obvious skeletal malformation of the upper distal limb in a patient with a known history of <a href="/articles/thalidomide-embryopathy" title="Thalidomide embryopathy">thalidomide</a>.</p><p>The illness known as <a href="/articles/thalidomide-embryopathy" title="Thalidomide embryopathy">thalidomide embryopathy</a>, which is caused by <em>in-utero</em> exposure to the drug, is distinguished by a number of foetal malformations. The majority of thalidomide exposure in foetuses happened between 1957 and 1961, when it was prescribed to pregnant women to relieve morning sickness.</p><p>It can lead to limb, facial and cardiac abnormalities or limited growth.</p>
Updates to Study Attributes
Findings
was changed:
Obvious skeletal malformation of the upper limb such as (phocomelia), radial ray anomalies with markedly hypoplastic radius,absent thumb and carpal bones, hypoplatichypoplastic curved ulna, and ulnar-metacarpal fusion.
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