Thalidomide phocomelia
Diagnosis certain
Disclosures
- updated 26 Feb 2024:
Nothing to disclose
Updates to Case Attributes
Status
changed from draft to pending review.
Presentation
was changed:
Cough and left arm pain.
Body
was changed:
Thalidomide associated phocomelia is a rare congenital abnormality secondary to maternal thalidomide use in the first trimester of pregnancy.
Associated congenital abnormalities include facial and cardiac anomalies but upper limb anomalies are prevailing.
Thalidomide was used in the late 1950s and early 1960s for treatment of morning sickness which resulted in baby's born with severe upper limb abnormalities when taken during early pregnancy. Thalidomide was banned shortly thereafter. Therefore all patients with the characteristic deformities were born within those years and are now in adulthood.
-<p>Thalidomide associated phocomelia is a rare congenital abnormality secondary to maternal thalidomide use in the first trimester of pregnancy. </p><p>Associated congenital abnormalities include facial and cardiac anomalies but upper limb anomalies are prevailing.</p><p>Thalidomide was used in the late 1950s and early 1960s for treatment of morning sickness which resulted in baby's born with severe upper limb abnormalities. Thalidomide was banned shortly thereafter. Therefore all patients with the characteristic deformities were born within those years and are now in adulthood.</p>- +<p>Thalidomide associated phocomelia is a rare congenital abnormality secondary to maternal thalidomide use in the first trimester of pregnancy.</p><p>Associated congenital abnormalities include facial and cardiac anomalies but upper limb anomalies are prevailing.</p><p>Thalidomide was used in the late 1950s and early 1960s for treatment of morning sickness which resulted in baby's born with severe upper limb abnormalities when taken during early pregnancy. Thalidomide was banned shortly thereafter. Therefore all patients with the characteristic deformities were born within those years and are now in adulthood.</p>