Thalidomide phocomelia

Case contributed by Simon Rupret , 13 Mar 2024
Diagnosis certain
Changed by Simon Rupret, 13 Mar 2024
Disclosures - updated 26 Feb 2024: Nothing to disclose

Updates to Case Attributes

Status changed from draft to pending review.
Presentation was changed:
Cough and left arm pain.
Body was changed:

Thalidomide associated phocomelia is a rare congenital abnormality secondary to maternal thalidomide use in the first trimester of pregnancy.

Associated congenital abnormalities include facial and cardiac anomalies but upper limb anomalies are prevailing.

Thalidomide was used in the late 1950s and early 1960s for treatment of morning sickness which resulted in baby's born with severe upper limb abnormalities when taken during early pregnancy. Thalidomide was banned shortly thereafter. Therefore all patients with the characteristic deformities were born within those years and are now in adulthood.

  • -<p>Thalidomide associated phocomelia is a rare congenital abnormality secondary to maternal thalidomide use in the first trimester of pregnancy. </p><p>Associated congenital abnormalities include facial and cardiac anomalies but upper limb anomalies are prevailing.</p><p>Thalidomide was used in the late 1950s and early 1960s for treatment of morning sickness which resulted in baby's born with severe upper limb abnormalities. Thalidomide was banned shortly thereafter. Therefore all patients with the characteristic deformities were born within those years and are now in adulthood.</p>
  • +<p>Thalidomide associated phocomelia is a rare congenital abnormality secondary to maternal thalidomide use in the first trimester of pregnancy.</p><p>Associated congenital abnormalities include facial and cardiac anomalies but upper limb anomalies are prevailing.</p><p>Thalidomide was used in the late 1950s and early 1960s for treatment of morning sickness which resulted in baby's born with severe upper limb abnormalities when taken during early pregnancy. Thalidomide was banned shortly thereafter. Therefore all patients with the characteristic deformities were born within those years and are now in adulthood.</p>

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