Carcinosarcoma of the ovary
Updates to Article Attributes
A carcinosarcoma of the ovary is a rare type of mixed ovarian tumour with both epithelial and stromal components.
Epidemiology
They are very rare and account for less than 1% of all ovarian cancers. Most women are post-menopausal at the time of presentation and usually between their 6th to 8th decades of life.
Clinical presentation
Patients often present with an abdominal mass, ascites, and anaemia. As with other ovarian tumours, the presentation can be vague.
Pathology
They are histologically biphasic tumours with both carcinomatous (epithelial) and sarcomatous (stromal) elements.
Radiographic features
On imaging, it is not possible to differentiate carcinosarcomas from other ovarian neoplasms and therefore the diagnosis is essentially based on histopathologic findings. Features common to ovarian neosplasmsneoplasms, in general, may be present.
A high incidence of haemorrhagic ascites has been reported in those with advanced disease 6 reported is >50% of the patients having ascites from the tumours.
Staging
The FIGO system is commonly used for staging: see ovarian cancer staging.
Treatment and prognosis
They are malignant aggressive neoplasms 1,3 carrying a poor prognosis even despite a combination of surgical debulking, radiation therapy, and chemotherapy. Metastasis is generally involves serosal and peritoneal seeding. Median survival rates reported in the literature range ~7-10 months at the time of initial writing 5.
See also
-<p>A <strong>carcinosarcoma of ovary</strong> is rare type of mixed <a href="/articles/ovarian-tumours">ovarian tumour </a>with both epithelial and stromal components.</p><h4>Epidemiology</h4><p>They are very rare and account for less than 1% of all ovarian cancers. Most women are post-menopausal at the time of presentation and usually between their 6<sup>th</sup> to 8<sup>th</sup> decades of life.</p><h4>Clinical presentation</h4><p>Patients often present with an abdominal mass, ascites, and anaemia. As with other ovarian tumours, presentation can be vague.</p><h4>Pathology</h4><p>They are histologically biphasic tumours with both carcinomatous (epithelial) and sarcomatous (stromal) elements.</p><h4>Radiographic features</h4><p>On imaging, it is not possible to differentiate carcinosarcomas from other ovarian neoplasms and therefore the diagnosis is essentially based on histopathologic findings. Features common to ovarian neosplasms in general may be present.</p><p>A high incidence of haemorrhagic ascites has been reported in those with advanced disease <sup>6</sup> reported is >50% of the patients having ascites from the tumours.</p><h5>Staging</h5><p>The FIGO system is commonly used for staging: see <a href="/articles/ovarian-cancer-staging">ovarian cancer staging</a>.</p><h4>Treatment and prognosis</h4><p>They are malignant aggressive neoplasms <sup>1,3</sup> carrying a poor prognosis even despite a combination of surgical debulking, radiation therapy, and chemotherapy. Metastasis is generally involves serosal and peritoneal seeding. Median survival rates reported in the literature range ~7-10 months at the time of initial writing <sup>5</sup>.</p><h4>See also</h4><ul><li><a href="/articles/malignant-mixed-mullerian-tumour">malignant mixed Mullerian tumours of the uterus</a></li></ul>- +<p>A <strong>carcinosarcoma of the ovary</strong> is a rare type of mixed <a href="/articles/ovarian-tumours">ovarian tumour </a>with both epithelial and stromal components.</p><h4>Epidemiology</h4><p>They are very rare and account for less than 1% of all ovarian cancers. Most women are post-menopausal at the time of presentation and usually between their 6<sup>th</sup> to 8<sup>th</sup> decades of life.</p><h4>Clinical presentation</h4><p>Patients often present with an abdominal mass, ascites, and anaemia. As with other ovarian tumours, the presentation can be vague.</p><h4>Pathology</h4><p>They are histologically biphasic tumours with both carcinomatous (epithelial) and sarcomatous (stromal) elements.</p><h4>Radiographic features</h4><p>On imaging, it is not possible to differentiate carcinosarcomas from other ovarian neoplasms and therefore the diagnosis is essentially based on histopathologic findings. Features common to ovarian neoplasms, in general, may be present.</p><p>A high incidence of haemorrhagic ascites has been reported in those with advanced disease <sup>6</sup> reported is >50% of the patients having ascites from the tumours.</p><h5>Staging</h5><p>The FIGO system is commonly used for staging: see <a href="/articles/ovarian-cancer-staging-1">ovarian cancer staging</a>.</p><h4>Treatment and prognosis</h4><p>They are malignant aggressive neoplasms <sup>1,3</sup> carrying a poor prognosis even despite a combination of surgical debulking, radiation therapy, and chemotherapy. Metastasis generally involves serosal and peritoneal seeding. Median survival rates reported in the literature range ~7-10 months at the time of initial writing <sup>5</sup>.</p><h4>See also</h4><ul><li><a href="/articles/malignant-mixed-mullerian-tumour">malignant mixed Mullerian tumours of the uterus</a></li></ul>
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