Diffuse T1 bone marrow signal loss
Disclosures
- updated 18 Jun 2022:
Nothing to disclose
Updates to Article Attributes
Body
was changed:
Diffuse T1 vertebral bone marrow signal loss is associated with replacement of fatty marrow by oedema or cellular tissue.
Radiographic features
MRI
T1-weighted imaging without fat suppression is one of the most important sequences for distinguishing between normal and abnormal bone marrow. Abnormal bone marrow is iso- or hypo-intense to skeletal marrowmuscle 3. In the case of homogeneous involvement, this appearance can often be difficult to spot as abnormal.
Differential diagnosis
- bone marrow hyperplasia
- myeloproliferative and lymphoproliferative diseases
- myelofibrosis
- diffuse bone metastases
- iron deposition related pathologies, e.g. haemochromatosis
- sarcoidosis
- spondyloarthropathy
- renal osteodystrophy
- gout
- gelatinous marrow conversion
-<p><strong>Diffuse T1 vertebral bone marrow signal loss</strong> is associated with replacement of fatty marrow by oedema or cellular tissue. </p><h4>Radiographic features</h4><h5>MRI</h5><p><a href="/articles/t1-weighted-image">T1-weighted imaging</a> without <a href="/articles/fat-suppressed-imaging">fat suppression</a> is one of the most important sequences for distinguishing between normal and abnormal <a href="/articles/bone-marrow">bone marrow</a>. Abnormal bone marrow is iso- or hypo-intense to skeletal marrow <sup>3</sup>. In the case of homogeneous involvement, this appearance can often be difficult to spot as abnormal. </p><h4>Differential diagnosis</h4><ul>- +<p><strong>Diffuse T1 vertebral bone marrow signal loss</strong> is associated with replacement of fatty marrow by oedema or cellular tissue. </p><h4>Radiographic features</h4><h5>MRI</h5><p><a href="/articles/t1-weighted-image">T1-weighted imaging</a> without <a href="/articles/fat-suppressed-imaging">fat suppression</a> is one of the most important sequences for distinguishing between normal and abnormal <a href="/articles/bone-marrow">bone marrow</a>. Abnormal bone marrow is iso- or hypo-intense to skeletal muscle <sup>3</sup>. In the case of homogeneous involvement, this appearance can often be difficult to spot as abnormal. </p><h4>Differential diagnosis</h4><ul>
Unable to process the form. Check for errors and try again.