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Dual-energy CT (clinical applications)

Changed by Joel Matthew Davies, 14 Apr 2023
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Disclosures - updated 14 Apr 2023: Nothing to disclose

Updates to Article Attributes

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Dual-energy CT or multispectral CT is becoming increasingly more common in clinical practice due to the rapid rise in computer technology and expanding literature exhibiting vast advantages over conventional single energy CT. 

Clinical applications

The clinical practice, adaptation and techniques of dual-energy CT is broken into individual articles:

  • virtual non-contrast imaging 

  • vascular 

    • automated bone removal in CT angiography 2

    • decrease metal device artifact 7

    • detection of endoleaks 7 

    • blood pool imaging 2

      • detection of pulmonary embolism

      • detection of myocardial ischaemia 

  • urinary system

    • characterisation of renal stones 2

    • characterisation of renal cysts and masses 2--44

  • neuroimaging

    • differentiation of haemorrhage from iodinated contrast

    • quantification of iodine leak in traumatic haemorrhagic contusions

    • bone removal

    • optimising imaging

  • ​female breast

    • identification of silicone leaks from breast implants 2

    • improved tumour conspicuity of breast cancers relative to conventional CT, with the potential determination of prognostic biomarkers such as ER and PR status 6

  • musculoskeletal

    • detection of bone marrow oedema

    • detection and quantification of urate crystals in gout

    • reduction of metal artifact 7

  • abdominal imaging

    • pancreatic diseases 5

  • thoracic imaging

    • detection of pulmonary thromboembolism; structural as well as functional information is obtained through iodine maps of pulmonary perfusion 7

    • assessment of a solitary pulmonary nodule to determine malignancy status 7,8

  • -<p><strong>Dual-energy CT </strong>or<strong> multispectral CT </strong>is becoming increasingly more common in clinical practice due to the rapid rise in computer technology and expanding literature exhibiting vast advantages over conventional single energy CT. </p><h4>Clinical applications</h4><p>The clinical practice, adaptation and techniques of <a href="/articles/dual-energy-ct-2">dual-energy CT </a>is broken into individual articles:</p><ul>
  • -<li>
  • -<a href="/articles/virtual-non-contrast-imaging">virtual non-contrast imaging</a> </li>
  • -<li>
  • -<a href="/articles/vascular-imaging-dual-energy-ct-1">vascular</a> <ul>
  • -<li>automated bone removal in CT angiography <sup>2</sup>
  • -</li>
  • -<li>decrease metal device artifact <sup>7</sup>
  • -</li>
  • -<li>detection of endoleaks <sup>7</sup> </li>
  • -<li>blood pool imaging <sup>2</sup><ul>
  • -<li>detection of pulmonary embolism</li>
  • -<li>detection of myocardial ischaemia </li>
  • -</ul>
  • -</li>
  • -</ul>
  • -</li>
  • -<li>
  • -<a href="/articles/urinary-system-imaging-dual-energy-ct-1">urinary system</a><ul>
  • -<li>characterisation of renal stones <sup>2</sup>
  • -</li>
  • -<li>characterisation of renal cysts and masses <sup>2-</sup><sup>4</sup>
  • -</li>
  • -</ul>
  • -</li>
  • -<li>
  • -<a href="/articles/neuroimaging-dual-energy-ct">neuroimaging</a><ul>
  • -<li>differentiation of haemorrhage from iodinated contrast</li>
  • -<li>quantification of iodine leak in traumatic haemorrhagic contusions</li>
  • -<li>bone removal</li>
  • -<li>optimising imaging</li>
  • -</ul>
  • -</li>
  • -<li>
  • -<sup>​</sup>female breast<ul>
  • -<li>identification of silicone leaks from <a href="/articles/breast-implants">breast implants</a> <sup>2</sup>
  • -</li>
  • -<li>improved tumour conspicuity of breast cancers relative to conventional CT, with the potential determination of prognostic biomarkers such as ER and PR status <sup>6</sup>
  • -</li>
  • -</ul>
  • -</li>
  • -<li>
  • -<a href="/articles/musculoskeletal-imaging-dual-energy-ct-1">musculoskeletal</a><ul>
  • -<li>detection of <a href="/articles/bone-marrow-edema">bone marrow oedema </a>
  • -</li>
  • -<li>detection and quantification of urate crystals in <a href="/articles/gout">gout </a>
  • -</li>
  • -<li>reduction of metal artifact <sup>7</sup>
  • -</li>
  • -</ul>
  • -</li>
  • -<li>
  • -<a href="/articles/abdominal-imaging-dual-energy-ct-1">abdominal imaging</a><ul><li>pancreatic diseases <sup>5</sup>
  • -</li></ul>
  • -</li>
  • -<li>thoracic imaging<ul>
  • -<li>detection of pulmonary thromboembolism; structural as well as functional information is obtained through <a title="iodine maps of pulmonary perfusion" href="/articles/iodine-maps-of-pulmonary-perfusion">iodine maps of pulmonary perfusion</a> <sup>7</sup>
  • -</li>
  • -<li>assessment of a solitary pulmonary nodule to determine malignancy status <sup>7,8</sup>
  • -</li>
  • -</ul>
  • -</li>
  • +<p><strong>Dual-energy CT </strong>or<strong> multispectral CT </strong>is becoming increasingly common in clinical practice due to the rapid rise in computer technology and expanding literature exhibiting vast advantages over conventional single energy CT. </p><h4>Clinical applications</h4><p>The clinical practice, adaptation and techniques of <a href="/articles/dual-energy-ct-2">dual-energy CT </a>is broken into individual articles:</p><ul>
  • +<li><p><a href="/articles/virtual-non-contrast-imaging">virtual non-contrast imaging</a> </p></li>
  • +<li>
  • +<p><a href="/articles/vascular-imaging-dual-energy-ct-1">vascular</a> </p>
  • +<ul>
  • +<li><p>automated bone removal in CT angiography <sup>2</sup></p></li>
  • +<li><p>decrease metal device artifact <sup>7</sup></p></li>
  • +<li><p>detection of endoleaks <sup>7</sup> </p></li>
  • +<li>
  • +<p>blood pool imaging <sup>2</sup></p>
  • +<ul>
  • +<li><p>detection of pulmonary embolism</p></li>
  • +<li><p>detection of myocardial ischaemia </p></li>
  • +</ul>
  • +</li>
  • +</ul>
  • +</li>
  • +<li>
  • +<p><a href="/articles/urinary-system-imaging-dual-energy-ct-1">urinary system</a></p>
  • +<ul>
  • +<li><p>characterisation of renal stones <sup>2</sup></p></li>
  • +<li><p>characterisation of renal cysts and masses <sup>2-4</sup></p></li>
  • +</ul>
  • +</li>
  • +<li>
  • +<p><a href="/articles/neuroimaging-dual-energy-ct">neuroimaging</a></p>
  • +<ul>
  • +<li><p>differentiation of haemorrhage from iodinated contrast</p></li>
  • +<li><p>quantification of iodine leak in traumatic haemorrhagic contusions</p></li>
  • +<li><p>bone removal</p></li>
  • +<li><p>optimising imaging</p></li>
  • +</ul>
  • +</li>
  • +<li>
  • +<p><sup>​</sup>female breast</p>
  • +<ul>
  • +<li><p>identification of silicone leaks from <a href="/articles/breast-implants">breast implants</a> <sup>2</sup></p></li>
  • +<li><p>improved tumour conspicuity of breast cancers relative to conventional CT, with the potential determination of prognostic biomarkers such as ER and PR status <sup>6</sup></p></li>
  • +</ul>
  • +</li>
  • +<li>
  • +<p><a href="/articles/musculoskeletal-imaging-dual-energy-ct-1">musculoskeletal</a></p>
  • +<ul>
  • +<li><p>detection of <a href="/articles/bone-marrow-edema">bone marrow oedema</a></p></li>
  • +<li><p>detection and quantification of urate crystals in <a href="/articles/gout">gout</a></p></li>
  • +<li><p>reduction of metal artifact <sup>7</sup></p></li>
  • +</ul>
  • +</li>
  • +<li>
  • +<p><a href="/articles/abdominal-imaging-dual-energy-ct-1">abdominal imaging</a></p>
  • +<ul><li><p>pancreatic diseases <sup>5</sup></p></li></ul>
  • +</li>
  • +<li>
  • +<p>thoracic imaging</p>
  • +<ul>
  • +<li><p>detection of pulmonary thromboembolism; structural as well as functional information is obtained through <a href="/articles/iodine-maps-of-pulmonary-perfusion" title="iodine maps of pulmonary perfusion">iodine maps of pulmonary perfusion</a> <sup>7</sup></p></li>
  • +<li><p>assessment of a solitary pulmonary nodule to determine malignancy status <sup>7,8</sup></p></li>
  • +</ul>
  • +</li>

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